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Vir Biotechnology (VIR) investor relations material

Vir Biotechnology Q2 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q2 2025 earnings summary6 Aug, 2025

Executive summary

  • Advanced hepatitis delta and oncology pipelines, with all ECLIPSE registrational studies enrolling and first patient dosed in Phase 1 study of VIR-5525 in July 2025, expanding the oncology pipeline to three ongoing Phase 1 studies.

  • Strategic realignment and restructuring led to cost savings, including phasing out certain research programs and site closures.

  • Diversified pipeline includes siRNA, antibody, and masked T-cell engager platforms, with multiple assets in Phase 1–3 trials.

  • No material legal proceedings or off-balance sheet arrangements reported.

  • Focus on immune system-based therapies for cancer and infectious diseases, with lead programs in oncology and hepatitis delta.

Financial highlights

  • Q2 2025 total revenues were $1.2M, down from $3.1M in Q2 2024; net loss for Q2 2025 was $111.0M, compared to $138.4M in Q2 2024.

  • R&D expenses for Q2 2025 were $97.5M, down from $105.1M in Q2 2024, reflecting restructuring savings.

  • SG&A expenses for Q2 2025 were $22.3M, down from $30.3M in Q2 2024, due to headcount reductions and restructuring.

  • Cash, cash equivalents, and investments totaled $892.1M as of June 30, 2025, with restricted cash of $95.2M.

  • Net cash consumed in Q2 2025 was $127.7M, including $50.5M in milestone payments; excluding these, net cash consumed was $77.2M.

Outlook and guidance

  • Cash runway projected into mid-2027, supporting advancement of key programs through value inflection points.

  • Focused on driving ECLIPSE study enrollment, advancing T cell engager programs, and executing business development strategies.

  • Anticipates providing 48-week Solstice study data by year-end and meaningful updates on T cell engager programs as data mature.

  • No significant revenue expected from sotrovimab or other product sales until regulatory approvals are obtained.

  • Multiple clinical catalysts anticipated, including pivotal HDV studies and Phase 1 oncology data.

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Frequently asked questions

Vir Biotechnology Inc., a commercial-stage immunology company, specializes in developing therapeutic products aimed at treating and preventing serious infectious diseases. Leveraging its expertise in immunology, Vir Biotechnology focuses on a wide range of diseases, including viral and bacterial infections, with a particular emphasis on chronic infectious diseases like hepatitis B, tuberculosis, and HIV, as well as respiratory diseases such as influenza, respiratory syncytial virus (RSV), and metapneumovirus (MPV). The company's approach involves a multi-program, multi-platform strategy to induce protective and therapeutic immune responses. Vir Biotechnology is headquartered in San Francisco, California, and its shares are listed on the Nasdaq.

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