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Viridian Therapeutics (VRDN) investor relations material
Viridian Therapeutics Q2 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q2 2025 earnings summary6 Aug, 2025
Executive summary
Veligrotug achieved positive phase 3 results in both active and chronic TED, meeting all endpoints with strong durability and safety, and received Breakthrough Therapy Designation in May 2025.
VRDN-003, a subcutaneous anti-IGF-1R, is advancing in phase 3 trials with topline data expected 1H 2026 and BLA submission by year-end 2026.
FcRn inhibitor portfolio (VRDN-006, VRDN-008) progressing toward clinical milestones, with proof-of-concept and IND submissions expected in 2025.
Exclusive license agreement with Kissei Pharmaceutical in Japan for TED portfolio: $70M upfront, $315M in milestones, and royalties.
Focused on developing best-in-class therapies for serious and rare diseases, targeting TED and autoimmune conditions.
Financial highlights
Cash, cash equivalents, and short-term investments totaled $563.4M as of June 30, 2025, supporting operations into 2H 2027.
Net loss was $100.7M for Q2 2025, up from $65.0M in Q2 2024; six-month net loss was $187.6M, up from $113.5M year-over-year.
R&D expenses rose to $86.6M in Q2 2025, driven by increased clinical trial and manufacturing costs.
G&A expenses increased to $20.2M in Q2 2025, reflecting higher headcount and commercialization preparation.
Collaboration revenue remained minimal at $75,000 for Q2 2025.
Outlook and guidance
BLA submission for veligrotug planned for 2H 2025; EU MAA in 1H 2026; potential U.S. launch in 2H 2026.
VRDN-003 topline phase 3 data expected 1H 2026, with BLA submission by year-end 2026.
VRDN-006 proof-of-concept data in Q3 2025; VRDN-008 IND submission by year-end 2025.
Cash runway expected to last into 2H 2027; additional capital will be required for future growth.
Veligrotug launch timeline with Priority Review?
VRDN-003's market positioning vs. veligrotug?
Assumptions for cash runway into 2H 2027?
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Next Viridian Therapeutics earnings date
Q3 202511 Nov, 2025
Next Viridian Therapeutics earnings date
Q3 202511 Nov, 2025
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Frequently asked questions
Viridian Therapeutics Inc. is a biotechnology company focused on developing treatments for patients with serious diseases, particularly those related to rare and underserved conditions. The company’s primary area of research includes therapies for thyroid eye disease (TED) and other autoimmune and inflammatory diseases. Viridian Therapeutics employs innovative biologics and small-molecule technologies to address unmet medical needs and improve patient outcomes through targeted therapeutic approaches. The company is headquartered in Waltham, Massachusetts, and its shares are listed on the NASDAQ.
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