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Zevra Therapeutics (ZVRA) investor relations material
Zevra Therapeutics 44th Annual J.P. Morgan Healthcare Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Strategic vision and values
Mission to redefine rare disease therapy and become a leading rare disease therapeutics company, driven by patient centricity, accountability, and innovation.
Focus on disciplined investment, leveraging a strong balance sheet and experienced team to drive sustainable growth.
Emphasis on not overextending resources, instead targeting high-value opportunities and building a culture dedicated to patient impact.
Values include integrity, innovation, and courage in delivering on commitments.
Financial performance and resources
Generated $72.3 million in net revenue in the first nine months of 2025, with $26.1 million in Q3.
Ended Q3 2025 with $230.4 million in cash, cash equivalents, and investments, and $61.3 million in debt.
Monetized a Pediatric Priority Review Voucher for $150 million, adding non-dilutive capital.
Maintains multiple revenue streams, including product sales, expanded access programs, and royalties.
Product portfolio and pipeline
Miplyffa, FDA-approved in September 2024 for Niemann-Pick disease type C (NPC), holds orphan drug exclusivity through 2031, with potential patent extension under review.
OLPRUVA for urea cycle disorders (IP through 2036) and AZSTARYS for ADHD (royalties/milestones through 2037) complement the portfolio.
Celiprolol in Phase III for vascular Ehlers-Danlos syndrome (vEDS), with IP through 2038 and ongoing pivotal DISCOVER trial.
KP1077 in late-stage development for idiopathic hypersomnia and narcolepsy.
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