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Zura Bio (ZURA) investor relations material
Zura Bio Cantor Global Healthcare Conference 2025 summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Cantor Global Healthcare Conference 2025 summary4 Sep, 2025
Company and lead program overview
Raised $200 million since NASDAQ listing in April 2023 and in-licensed three bispecific monoclonal antibodies.
Lead asset, tibulizumab, targets both IL-17 and B-cell activating factor, currently in two Phase II studies for systemic sclerosis and hidradenitis suppurativa.
Top-line data from both studies expected in Q3–Q4 of next year.
Scientific and clinical rationale
IL-17 component (ixekizumab) has high affinity for 17A and 17AF, with a unique combination approach expected to yield robust results.
B-cell activating factor is upregulated in hidradenitis suppurativa, with supporting evidence from other B-cell targeting agents.
Systemic sclerosis pathogenesis involves IL-17A-driven inflammation and fibrosis; prior studies with IL-17 receptor agents provide supportive data.
Phase II study designs and endpoints
Hidradenitis suppurativa study: 16-week duration, two active arms (low/high dose), primary endpoint is change in AN count, with secondary endpoints including HiSCR and DLQI.
Systemic sclerosis study: 24-week duration, high dose only, primary endpoint is change in modified Rodnan skin score, with secondary endpoints including FVC and high-res CT scan.
Both studies include loading doses and are designed to inform Phase III dosing and strategy.
How will tibulizumab differentiate from current IL-17s?
What is the strategy for non-lead pipeline assets?
How will Zura Bio fund costly Phase III trials?
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Next Zura Bio earnings date
Q3 20257 Nov, 2025
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Frequently asked questions
Zura Bio Limited is a clinical-stage biotechnology company focused on developing innovative therapies for immune and inflammatory disorders. It leverages multi-asset immunology to create novel dual-pathway antibodies, including tibulizumab, ZB-168, and torudokimab, which are designed to address autoimmune diseases and other conditions with unmet medical needs. These therapies have completed early-phase studies and are advancing towards further clinical development. Zura Bio Limited is headquartered in Henderson, Nevada, and its shares are listed on NASDAQ.
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