)
Zura Bio (ZURA) investor relations material
Zura Bio Guggenheim Securities Emerging Outlook: Biotech Summit 2026 summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Leadership and strategic focus
Newly appointed CEO with prior involvement as founder and board member, emphasizing transition from execution to data-driven company.
Main focus on advancing tibulizumab, a bispecific antibody targeting IL-17A and BAFF, for autoimmune inflammatory disorders.
Two key phase II readouts expected: hidradenitis suppurativa (Q4 this year) and systemic sclerosis (first half 2027).
Capital allocation is prioritized, with additional assets (IL-7 receptor antibody and IL-33 antibody) in early focus but not yet funded for trials.
Future indications are under consideration, balancing orphan and broader populations, with updates expected later this year.
Clinical development and pipeline
Tibulizumab is engineered from Eli Lilly’s tabalumab and ixekizumab, combining validated targets for enhanced efficacy.
Phase II hidradenitis suppurativa study expanded to 225 patients, focusing on robust data quality and minimizing placebo response.
Dosing regimen involves initial loading followed by monthly administration, with high predicted target engagement.
Immunogenicity rates are low (<5%), attributed to strong bioengineering and balanced target affinity.
Additional pipeline assets include crebankitug (IL-7R antibody from Pfizer) and torudokimab (IL-33 antibody from Lilly).
Scientific rationale and disease focus
Hidradenitis suppurativa chosen due to complex, heterogeneous biology; both IL-17 and B-cell/BAFF pathways implicated.
Recent clinical data from other B-cell targeted therapies (e.g., ianalumab, remibrutinib, iscalimab) support the approach.
Study design excludes prior IL-17 failures but allows up to 30% TNF failures; primary endpoint is reduction in abscess and nodule count, with HiSCR 75 as a key secondary.
Systemic sclerosis trial targets diffuse subtype with significant skin and lung involvement, using modified Rodnan skin score and AI-based HRCT for endpoints.
Standard of care (e.g., MMF, methotrexate) is allowed if stable, ensuring real-world applicability.
Next Zura Bio earnings date
Next Zura Bio earnings date
The essential earnings season companion
The #1 app for qualitative research. Live earnings calls, AI chat, transcripts, and more. All for free.
Live calls and transcripts
Listen to earnings calls, CMDs, investor conferences, and more – with a podcast-like experience.
Find what you need faster
Search for any keyword across all transcripts simultaneously.
Easily store key findings
Capturing important takeaways is as simple as it gets. Even during your lunch run or commute.
Your watchlist. Your dashboard.
Follow the companies that matter to you. Get a personalized feed with real-time updates.
Be the first to know
Set keyword alerts for any company, product, or competitor. Get notified the moment they're mentioned.
Consensus estimates
Access analyst consensus estimates, valuation multiples, and revenue segments splits.
All IR material in one place
The easiest way to stay updated during earnings season.
Global coverage
All events from public companies. Live and recorded.
Just click and listen
No webcast links. No manual registrations.
excellent app, it gives me free access to company earnings calls and annual reports. I also love the convenience of calls being available offline so I can listen in whilst doing other things and even when internet or WiFi isn't available.
One of the very few apps you could call perfect. If something was to add to it, maybe the share price of the company when you search for it, but it's already excellent.
This is genuinely one of the cleanest and fastest finance apps out there to track the market.
excellent app, it gives me free access to company earnings calls and annual reports. I also love the convenience of calls being available offline so I can listen in whilst doing other things and even when internet or WiFi isn't available.
One of the very few apps you could call perfect. If something was to add to it, maybe the share price of the company when you search for it, but it's already excellent.
This is genuinely one of the cleanest and fastest finance apps out there to track the market.
I can't remember the last time an app had such a positive impact on my investment process.
Love the app! Quartr makes it really easy to keep track of earnings calls. It also includes the reports and slides to make it easier to follow along.
Quartr is amazing, no way around it. It is the best right now for earnings calls, presentations, and the like.
I can't remember the last time an app had such a positive impact on my investment process.
Love the app! Quartr makes it really easy to keep track of earnings calls. It also includes the reports and slides to make it easier to follow along.
Quartr is amazing, no way around it. It is the best right now for earnings calls, presentations, and the like.
Frequently asked questions
Mobile app: Research anytime, anywhere with the #1 app for live earnings calls, transcripts, analyst estimates, and more. All for free.
Desktop (Quartr Pro): The leading platform for qualitative research, used daily by top firms and financial institutions.
Quartr API: Build custom solutions powered by live earnings calls, live transcripts, filings and reports, slide presentations, and more.
Explore our global coverage
)
)