Logotype for Illumina Inc

Illumina (ILMN) Q3 2024 earnings summary

Event summary combining transcript, slides, and related documents.

Logotype for Illumina Inc

Q3 2024 earnings summary

16 Jan, 2026

Executive summary

  • Q3 2024 revenue was $1.08 billion, in line with expectations, with strong margin and earnings expansion driven by operational excellence and cost discipline.

  • Non-GAAP operating margin was 22.6% and diluted EPS was $1.14, both exceeding guidance.

  • NovaSeq X adoption accelerated, with over 55% of high-throughput gigabases sequenced on X and cumulative NovaSeq X revenue surpassing $1 billion.

  • GRAIL was spun off in June 2024, with 85.5% of shares distributed to stockholders and 14.5% retained.

  • The company launched the MiSeq i100 and announced further innovations, including comprehensive whole genome sequencing and five-base genome technology.

Financial highlights

  • Sequencing consumables revenue grew 7% year-over-year to $741 million, offsetting a 42% decline in sequencing instruments revenue.

  • Total sequencing gigabase output grew over 40% year-over-year.

  • Non-GAAP gross margin increased 450 basis points year-over-year to 70.5%, driven by productivity improvements and favorable revenue mix.

  • Free cash flow was $284 million, with $316 million in cash flow from operations.

  • Q3 2024 net income was $705 million GAAP and $181 million non-GAAP.

Outlook and guidance

  • Full-year 2024 revenue is expected to decline approximately 3%, with Q4 revenue projected at $1.07 billion.

  • Non-GAAP operating margin guidance raised to 21%-21.5% for 2024; non-GAAP diluted EPS guidance increased to $4.05-$4.15.

  • Instrument revenue is forecasted to decline in the mid-30% range versus 2023, while consumables revenue is expected to grow toward the upper end of low single digits.

  • Positive growth is anticipated in 2025, with a return to high single-digit revenue growth by 2027.

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