iRhythm Technologies (IRTC) 44th Annual J.P. Morgan Healthcare Conference summary

Strategic Vision and Market Dynamics

• Emphasizing proactive arrhythmia detection, leveraging AI and 3 billion hours of heartbeat data to identify undiagnosed patients, especially in comorbid disease states.

• Significant market opportunity with 27 million undiagnosed individuals in the U.S. and less than 1% market share internationally, targeting expansion in both core and adjacent markets like sleep and hypertension.

• Heart rhythm disorders are highly prevalent in the aging population, with significant gaps in access to cardiologists, especially in rural areas.

• Trends such as increased arrhythmia awareness, new therapies, and value-based care are expanding the total addressable market.

• Primary care channel now represents over a third of business, with innovative partnerships and digital integration driving growth and access.

Technology, Product Innovation, and Competitive Positioning

• Platform features patented wearable biosensors, advanced AI-driven ECG detection, and seamless EHR integration.

• Second-generation FDA-approved AI algorithm in use, with a third-generation algorithm under FDA review, aiming for enhanced diagnostic precision.

• Next-generation MCT device submitted for FDA clearance, offering improved form factor, longer wear, and enhanced detection algorithms.

• AI and digital workflow tools, such as ZioSuite, streamline prescribing and diagnosis, supporting both primary care and specialist adoption.

• Competitors face challenges entering primary care due to cost structure, while integration and product differentiation provide strong customer retention.

Market Leadership and Growth Opportunities

• Holds 72% market share in long-term continuous monitoring (LTCM) and 15% in mobile cardiac telemetry (MCT) in the US.

• Penetration in the US ambulatory cardiac monitoring market reached ~40% by end of 2025.

• International expansion underway in the UK, select EU countries, and Japan, with goals to embed products in clinical practice and secure contracts.

• Innovative partnerships with virtual care, primary care, and value-based care models drive early engagement and risk identification.

• EHR integrations streamline workflows, with over half of registration volumes from integrated accounts.