Xilio Therapeutics (XLO) Registration filing summary

Company overview and business model

• Clinical-stage biotechnology company developing masked immuno-oncology therapies to improve cancer outcomes and reduce systemic side effects.

• Uses a clinically-validated masking technology to activate biologics within the tumor microenvironment.

• Advancing multiple preclinical and clinical programs, including masked multi-specifics, and has established strategic partnerships.

Financial performance and metrics

• As of May 26, 2026, public float was approximately $57.6 million, based on 6,575,139 outstanding shares and a price of $8.81 per share.

• Net tangible book value as of March 31, 2026, was $72.5 million ($12.55 per share); pro forma as adjusted after offering would be $4.14 per share.

• Immediate dilution to new investors in the offering is estimated at $4.21 per share.

Use of proceeds and capital allocation

• Net proceeds from securities sales will be used for general corporate purposes, including R&D, clinical trials, acquisitions, development and commercial capabilities, personnel, collaborations, working capital, and capital expenditures.

• Proceeds may be temporarily invested in short-term, investment-grade, interest-bearing instruments or U.S. government securities.

• Management has broad discretion over allocation of proceeds.