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Absci (ABSI) investor relations material

Absci Jefferies London Healthcare Conference 2025 summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Jefferies London Healthcare Conference 2025 summary18 Nov, 2025

Strategic focus and AI platform

  • Focused on generative AI for drug discovery, targeting undruggable diseases with known biology.

  • Proprietary models enable de novo antibody design, optimizing for binding affinity, human naturalness, and multiparametric objectives, with rapid transition from in silico to wet lab validation.

  • Multidisciplinary team leverages a data flywheel from a 77,000 sq ft automated wet lab, generating hundreds of millions of sequence-function datapoints since 2020.

  • Team includes AI talent from leading tech companies and scientists with 10+ approved drugs.

  • Proprietary model allows precise engineering of antibody function, supporting both internal development and partnerships.

Financial position and partnerships

  • $150 million in cash as of Q3, providing runway into early 2028.

  • Collaborations with major pharma (AstraZeneca, Merck), tech (NVIDIA, AMD), and 25+ partnered programs with pharma, academic, and tech organizations; AMD invested $20 million.

  • Ongoing and anticipated new pharma partnerships expected within the next year, with further partnerships anticipated in 2025/2026.

Pipeline and clinical development

  • ABS-201 for androgenetic alopecia: Accelerated Ph1/2a trial to start December, with interim efficacy readout expected in the second half of next year.

  • ABS-201 for endometriosis: Phase 2 PoC study anticipated to initiate Q4 2026, with interim efficacy readout as early as 2H2027.

  • Additional pipeline assets include ABS-101 (IBD, completed phase 1 and being considered for out-licensing), ABS-501 (oncology), and ABS-301 (immuno-oncology), with early discovery programs ongoing.

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Frequently asked questions

Absci Corporation operates as a generative AI drug creation company, focusing on revolutionizing the process of biologics drug discovery. Leveraging an integrated drug creation platform, Absci identifies novel drug targets and creates biotherapeutic candidates, shifting from traditional drug discovery to drug creation. This approach enables the design of de novo antibodies directly on computers, potentially reducing the development time for new drug leads and increasing their probability of success. The company's platform combines artificial intelligence with synthetic biology, allowing the construction and testing of millions of AI designs weekly. This innovative process results in wet lab-validated biologic-based therapeutics in a significantly shortened timeframe, aiming to address the challenges of traditionally high failure rates and lengthy development times in biologics drug discovery. The company is headquartered in Vancouver, Washington, and its shares are listed on the Nasdaq.

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