AC Immune
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AC Immune (ACIU) investor relations material

AC Immune Q3 2026 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2026 earnings summary4 Nov, 2026

Executive summary

  • ACI-7104 reported positive Part 1 week-100 safety and immunogenicity results in Phase 2 VacSYn; the program also received FDA Fast Track designation and IND clearance.

  • A lead Morphomer small-molecule candidate targeting alpha-synuclein was selected and entered preclinical development; ACI-19764 Phase 1 results showed safety, tolerability and CSF penetration.

Financial highlights

  • Q3 2026 revenue was CHF 3.244M vs CHF 0.939M in Q3 2025, reflecting Takeda arrangement revenue, including additional consideration for the AD4 Cohort.

  • Q3 R&D expense was CHF 9.853M vs CHF 13.071M; lower personnel, operational and discovery/preclinical spending partly offset a CHF 1.0M net increase in clinical program costs.

  • Q3 G&A expense was CHF 3.522M vs CHF 3.567M; operating loss narrowed to CHF 9.801M from CHF 16.166M, and net loss narrowed to CHF 8.750M from CHF 15.858M.

  • 9M 2026 revenue was CHF 19.476M vs CHF 3.235M; operating loss was CHF 23.397M vs CHF 54.924M, and net loss was CHF 21.678M vs CHF 56.074M.

Outlook and guidance

  • Cash resources are expected to fund operations into Q1 2028, excluding potential milestone payments.

  • ACI-7104 antibody characterization, including alpha-synuclein binding properties, was anticipated before year-end 2026; FDA discussions on the future development path were planned for early 2027.

  • Initial ACI-19764 Phase 1b results in patients with elevated hsCRP were expected in early 2027.

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Frequently asked questions

AC Immune SA is a clinical-stage biopharmaceutical company that specializes in precision medicine for neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and NeuroOrphan diseases. These candidates target the misfolded proteins associated with these diseases, aiming to diagnose, treat, and prevent neurodegeneration. AC Immune SA is headquartered in Lausanne, Switzerland, and its shares are listed on the Nasdaq.