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ACADIA Pharmaceuticals (ACAD) investor relations material
ACADIA Pharmaceuticals Q3 2026 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Q3 GAAP revenue was $342.3M, up 23% YoY; adjusted-basis growth was 22%, with DAYBUE and NUPLAZID sales growth.
Operating income rose to $71.7M from $35.8M; net income declined to $53.5M from $71.8M amid a less favorable tax comparison.
DAYBUE guidance increased, while RADIANT results informed a 60 mg-focused phase III plan for remlifanserin.
Financial highlights
Q3 revenue was $342.3M vs. $278.6M GAAP in Q3 2025; compared with adjusted prior-year revenue of $280.9M, growth was 22%.
DAYBUE net sales were $140.1M vs. $101.1M; NUPLAZID net sales were $202.2M vs. $179.8M adjusted, or $177.5M GAAP.
R&D expense was $76.3M vs. $87.8M; SG&A was $159.2M vs. $133.4M, reflecting commercial investment and lower spending on completed studies.
Q3 diluted EPS was $0.31 vs. $0.42; income tax expense was $26.9M vs. a $27.2M tax benefit in Q3 2025.
Outlook and guidance
FY26 total revenue guidance is $1.265B–$1.295B; DAYBUE global net sales guidance rose to $505M–$520M from $480M–$510M.
FY26 NUPLAZID net sales guidance is $760M–$775M; gross-to-net guidance is 23%–24% for DAYBUE and 22%–23% for NUPLAZID.
FY26 R&D expense guidance is $325M–$340M, reduced from $355M–$380M; SG&A guidance is $665M–$685M.
Phase 2 readouts are expected in 2H 2027 for ACP-211 in MDD and Q4 2027 for remlifanserin in LBDP; ACP-711 essential tremor Phase 2 is expected to begin in 2027.
- Priority review and launch preparations advanced as 2015 net loss reached $164.4M.ACAD
Q4 2015 - NUPLAZID launched; $529.0 million in cash supported an expanded CNS pipeline.ACAD
Q4 2016 - NUPLAZID sales surged, but rising launch and pipeline costs drove a $289.4 million net loss.ACAD
Q4 2017 - NUPLAZID growth funded a broader pipeline, but losses and commercialization risks remained.ACAD
Q4 2018 - NUPLAZID grew 52%, while pivotal pipeline progress met ongoing execution and funding risks.ACAD
Q4 2019 - NUPLAZID sales grew 30%, while losses widened and DRP approval faced an FDA setback.ACAD
Q4 2020 - NUPLAZID growth and positive Rett results advanced the pipeline amid pandemic and regulatory risks.ACAD
Q4 2021 - Higher R&D widened losses as sales grew; DAYBUE approval opened a second growth front.ACAD
Q4 2022 - FY23 revenue rose 40% to $726.4M as DAYBUE launched and net loss narrowed.ACAD
Q4 2023
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Next ACADIA Pharmaceuticals earnings date
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