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ACADIA Pharmaceuticals
ACADIA Pharmaceuticals (ACAD) investor relations material
ACADIA Pharmaceuticals Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q4 2025 earnings summary25 Feb, 2026
Executive summary
Achieved record adjusted revenues of $1.08B in 2025 (up 14% YoY) and GAAP revenues of $1.07B (up 12% YoY), with Q4 adjusted revenues of $298M (up 16% YoY) and GAAP revenues of $284M (up 9% YoY).
Both NUPLAZID and DAYBUE delivered strong double-digit sales growth in 2025, driven by increased demand, expanded market reach, and new product launches.
2025 marked the first year annual revenues exceeded $1B, reflecting robust commercial execution and positioning for sustained growth.
Net income for Q4 2025 was $274M, including a $250M non-cash tax benefit; full-year net income was $391M.
Pipeline momentum continues with multiple Phase 2 and 3 studies planned or underway, targeting large neurological and rare disease markets.
Financial highlights
Q4 2025 non-GAAP adjusted NUPLAZID sales: $189M (+17% YoY); FY25: $692M (+15% YoY).
Q4 2025 DAYBUE net sales: $110M (+13% YoY); FY25: $391M (+12% YoY).
Q4 2025 EPS (diluted): $1.60 (+86% YoY); FY25 EPS: $2.30 (+69% YoY).
R&D expenses Q4: $85M (down from $101M YoY); FY25: $329M.
SG&A Q4: $156M (up from $130M YoY); FY25: $549M.
Year-end cash and investments: $820M.
Outlook and guidance
2026 total revenue guidance: $1.22B–$1.28B.
NUPLAZID 2026 net sales expected at $760M–$790M; DAYBUE at $460M–$490M.
R&D expense guidance for 2026: $385M–$410M; SG&A: $660M–$700M.
Anticipates full launch of DAYBUE STIX in early Q2 2026 and Phase 2 remlifanserin study results in Alzheimer's disease psychosis between August and October 2026.
Long-term projections: NUPLAZID targeting $1B in annual sales by 2028; DAYBUE targeting $700M global net sales by 2028, with EU sales <15% of total.
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Next ACADIA Pharmaceuticals earnings date
TD Cowen 46th Annual Health Care Conference2 Mar, 2026
ACADIA Pharmaceuticals
Next ACADIA Pharmaceuticals earnings date
TD Cowen 46th Annual Health Care Conference2 Mar, 2026
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Frequently asked questions
ACADIA Pharmaceuticals Inc is a biopharmaceutical company that focuses on the development and commercialization of therapies addressing central nervous system disorders. The company offers treatments for conditions such as Parkinson’s disease psychosis and other neurological diseases. ACADIA operates within the healthcare sector, concentrating on innovative solutions for underserved medical needs. The company is headquartered in San Diego, California, and its shares are listed on the NASDAQ.
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