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Achilles Therapeutics (ACHL) investor relations material

Achilles Therapeutics Q3 2024 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2024 earnings summary14 Nov, 2024

Executive summary

  • Discontinued TIL-based cNeT program and closed Phase I/IIa CHIRON and THETIS trials; exploring strategic options with BofA Securities as advisor.

  • Cash position of $86.1 million as of September 30, 2024, plus $12.8 million R&D tax credit received in October.

Financial highlights

  • Cash and cash equivalents declined to $86.1 million from $131.5 million at year-end 2023.

  • R&D expenses rose to $16.4 million in Q3 2024 from $14.7 million in Q3 2023.

  • G&A expenses decreased to $4.0 million in Q3 2024 from $4.4 million in Q3 2023.

  • Net loss widened to $19.6 million ($0.48/share) in Q3 2024 from $16.7 million ($0.42/share) in Q3 2023.

  • Comprehensive loss for Q3 2024 was $13.5 million, reflecting a $6.1 million foreign exchange gain.

Outlook and guidance

  • Management is reviewing strategic options, including engagement with third parties developing alternative modalities for targeting clonal neoantigens.

  • Forward-looking statements highlight expectations for cash runway, operating expenses, and capital requirements.

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Frequently asked questions

Achilles Therapeutics plc is a biopharmaceutical company based in the United Kingdom, focused on developing precision T cell therapies targeting cancer. Using its proprietary platform, Achilles designs therapies that target clonal neoantigens—unique markers on tumor cells—enabling a personalized approach to treatment. The company’s therapeutic programs are primarily aimed at treating solid tumors, including lung and melanoma cancers. The company is headquartered in London, United Kingdom, and its shares are listed on the NASDAQ.

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