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Adaptive Biotechnologies (ADPT) investor relations material

Adaptive Biotechnologies Piper Sandler 37th Annual Healthcare Conference summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Piper Sandler 37th Annual Healthcare Conference summary3 Dec, 2025

Gross margin improvements and operational leverage

  • Achieved a 2% gross margin improvement in Q3, moving from 63% to 65% following the X transition.

  • Expecting a 5%-8% margin lift over the next 12 months post-launch, with further increases into the first half of 2026 as volume grows.

  • Operational leverage will be driven by increased volume and extra capacity from the X transition.

  • OpEx investments will focus on EMR integration, reimbursement workflow improvements, and commercial growth, with only modest additional investments anticipated.

Key growth drivers and EMR integration

  • EMR integration ranked as the largest contributor to growth, enhancing both volume and customer retention.

  • Blood-based testing is the second largest driver, increasing test frequency and adoption in community settings.

  • Community penetration and improved clinical guidelines also significantly support growth.

  • Over 165 sites integrated with EMR by end of Q3, with 40% of volume now processed through integrated flows.

  • Six of the top 10 accounts are now EMR integrated, leading to substantial volume increases post-integration.

Blood-based testing and clinical adoption

  • Blood-based testing enables more frequent monitoring compared to bone marrow, especially valuable in myeloma and DLBCL.

  • In myeloma, blood testing complements bone marrow and can reduce the need for invasive procedures.

  • Academic clinicians require data to shift to blood-based MRD, while community clinicians are more readily adopting it.

  • Data shows clonoSEQ in blood is more predictive than traditional M protein tests.

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Q4 202513 Feb, 2026
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Frequently asked questions

Adaptive Biotechnologies Corporation operates as a commercial-stage biotechnology company. It provides immunosequencing and immunodiagnostic solutions. Furthermore the company offers research and development, and customer-focused services primarily to academic, government, pharmaceutical, biotechnology, hospital/clinical laboratories, and other companies in the United States and internationally. It operates in two segments, Adaptive Diagnostics and Adaptive Therapeutics. The company's immune system platform analyzes and interprets T cell and B cell receptor sequencing data.

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