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Adaptive Biotechnologies (ADPT) investor relations material
Adaptive Biotechnologies Morgan Stanley 23rd Annual Global Healthcare Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
Key accomplishments and strategic goals
Achieved EBITDA profitability, Flatiron EMR integration, and NovaSeq X implementation ahead of schedule in 2024.
Focused on increasing market penetration, especially in community settings, and driving volume growth.
Implemented a multi-pronged strategy: EMR integration, blood-based testing, data generation, and partnerships like NeoGenomics.
Split sales force to target academic and community accounts, with national strategic account overlay.
Market penetration and growth drivers
MRD market penetration: 12% in multiple myeloma, 28% in ALL, 7% in MCL, 5% in CLL, and 3% in DLBCL.
1,500 of 3,700 ordering physicians are in the community, with community segment showing fastest growth at 16% QoQ.
Blood-based testing now 44% of MRD volume, up from 40% in Q2 2024, with ongoing R&D to improve test performance.
EMR integration at major accounts drives 84% YoY growth vs. 46% for non-integrated accounts.
Testing frequency and clinical utility
Testing frequency varies: 3.5–4 tests/year in ALL, 2–2.5 in multiple myeloma, 1 in CLL, MCL, and DLBCL.
80% of community oncologists use serial testing via EMR, expected to increase test frequency.
Clinical utility trials (MASTER, MIDUS) show MRD status can guide therapy decisions, supporting increased test adoption.
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