Addex Therapeutics
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Addex Therapeutics (ADXN) investor relations material

Addex Therapeutics Q2 2026 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q2 2026 earnings summary28 Sep, 2026

Executive summary

  • Raised $2.8 million via ATM facility, extending cash runway into Q4 2027 and supporting advancement of the in-house GABAB cough program toward clinical development.

  • Regained full rights to the GABAB PAM program from Indivior, enabling broad development opportunities across multiple indications.

  • Retained 20% equity in Neurosterix, which is advancing its M4 PAM program for schizophrenia with phase I data expected in Q4 2026.

  • Divested discovery platform to Neurosterix, retaining access to R&D staff at zero cost.

  • Pipeline includes dipraglurant for brain injury recovery, ADX-71149 for new indications, and ongoing discussions with potential partners.

Financial highlights

  • Net loss for H1 2026 was CHF 3.5 million, slightly higher than CHF 3.4 million in H1 2025.

  • Cash and cash equivalents at June 30, 2026, were CHF 0.8 million, down from CHF 1.6 million at year-end 2025.

  • Operating loss for H1 2026 was CHF 1.1 million, down from CHF 1.3 million in H1 2025, mainly due to reduced outsourced R&D.

  • Share of net loss from Neurosterix was CHF 2.3 million in H1 2026, up from CHF 2.1 million in H1 2025.

  • Raised CHF 2.3 million post-period through share sales.

Outlook and guidance

  • Cash runway secured into Q4 2027 following recent fundraising, but material uncertainty remains regarding going concern due to the need for additional capital.

  • IND filing planned for SUD program; IND-enabling studies for cough program pending financing.

  • Neurosterix's NTX-253 phase I data expected in Q4 2026; backup M4 PAM and mGlu7 NAM programs advancing.

  • Preparing dipraglurant for phase II in post-stroke recovery.

  • Exploring new indications and potential partnerships for ADX-71149 and mGlu2 PAM program.

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Frequently asked questions

Addex Therapeutics Ltd is a biotechnology company focused on the discovery and development of small molecule therapies for neurological disorders. The company specializes in allosteric modulators, a drug discovery approach aimed at targeting specific receptors in the central nervous system to treat conditions such as Parkinson’s disease, epilepsy, and schizophrenia. Addex conducts clinical and preclinical research to advance its pipeline of investigational treatments. The company is headquartered in Geneva, Switzerland, and its shares are listed on the SIX Swiss Exchange.