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Adicet Bio (ACET) investor relations material
Adicet Bio Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q3 2025 earnings summary5 Nov, 2025
Executive summary
Positive preliminary Phase 1 data for ADI-001 in lupus nephritis and SLE, with rapid and sustained reductions in disease activity and improved renal function; plans to initiate a Phase 2 pivotal trial in 2026.
Ongoing enrollment in Phase 1 studies for ADI-001 in multiple autoimmune indications, including LN, SLE, SSc, IIM, SPS, AAV, and treatment-refractory RA.
Regulatory filing for ADI-212 in metastatic castration-resistant prostate cancer planned for Q1 2026, with initial clinical data expected in 2H 2026.
Discontinued ADI-270 to prioritize resources on ADI-001 and ADI-212.
Completed $74.8 million capital raise in October 2025, extending cash runway into 2H 2027.
Financial highlights
Net loss for Q3 2025 was $26.9 million ($0.29 per share), a 12% improvement year-over-year; nine-month net loss was $86.3 million.
Operating expenses for Q3 2025 decreased 16% year-over-year to $28.0 million, with R&D at $22.9 million and G&A at $5.1 million.
Cash, cash equivalents, and short-term investments totaled $103.1 million as of September 30, 2025, with an additional $74.8 million raised in October 2025.
Outlook and guidance
Cash runway expected to fund operations into the second half of 2027, based on current cash and recent equity raise.
Clinical updates from Phase 1 studies of ADI-001 in LN, SLE, and SSc expected in 1H 2026; update for RA anticipated in 2H 2026.
Regulatory filing for ADI-212 in mCRPC planned for Q1 2026, with initial clinical data expected in 2H 2026.
What indications will the ADI-001 pivotal trial cover?
What is the goal of ADI-001 RA conditioning study?
What are ADI-212's key design enhancements?
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Next Adicet Bio earnings date
Guggenheim Securities 2nd Annual Healthcare Innovation Conference11 Nov, 2025
Next Adicet Bio earnings date
Guggenheim Securities 2nd Annual Healthcare Innovation Conference11 Nov, 2025
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Frequently asked questions
Adicet Bio Inc. is a clinical-stage biotechnology company focused on the discovery and development of allogeneic gamma delta T cell therapies for cancer and other diseases. The company specializes in creating off-the-shelf genetically modified gamma delta T cells that selectively target tumors, leveraging the unique properties of these cells to offer a new generation of immune cell therapy. The company is headquartered in Redwood City, California, and its shares are listed on the Nasdaq.
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