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AEON Biopharma (AEON) investor relations material

AEON Biopharma Q3 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2025 earnings summary14 Nov, 2025

Executive summary

  • Focus shifted to developing ABP-450 as a biosimilar to Botox for therapeutic indications after discontinuing Phase 2 migraine trials due to lack of efficacy and to preserve cash.

  • Positive biosimilarity data for ABP-450 confirmed identical amino-acid sequencing and highly similar functional characteristics to BOTOX, supporting the biosimilar strategy and global market positioning.

  • FDA Type 2a meeting is scheduled for November 19, 2025, to review analytical study results and development plan.

  • Management transition occurred in April 2025, with Robert Bancroft appointed as CEO.

  • Two strategic financing transactions—a $6 million PIPE and a Daewoong note exchange—are expected to reduce outstanding debt by over 90%, strengthen the balance sheet, and extend the cash runway into Q2 2026.

Financial highlights

  • Net loss for Q3 2025 was $4.5 million, and for the nine months ended September 30, 2025, net loss was $2.1 million, compared to net income of $39.9 million for the same period in 2024 (driven by non-recurring items).

  • Cash and cash equivalents were $5.9 million as of September 30, 2025, excluding proceeds from the November PIPE financing.

  • Total current assets increased to $7.4 million as of September 30, 2025, from $1.6 million at December 31, 2024.

  • SG&A expenses decreased 36% year-over-year for Q3 2025, and R&D expenses decreased 40% for the same period, reflecting cost-cutting and program wind-downs.

  • Significant non-cash items included a $75.6 million loss on warrant issuance and $86.0 million income from change in fair value of warrants in 2025.

Outlook and guidance

  • Cash position, including recent financing, is expected to fund operations through the second quarter of 2026.

  • Additional funding will be required for further development of ABP-450 and to maintain operations beyond Q2 2026.

  • Management has concluded there is substantial doubt about the ability to continue as a going concern without new capital.

  • Upcoming FDA Type 2a meeting on November 19, 2025, will determine the path forward for ABP-450 biosimilar development.

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Frequently asked questions

AEON Biopharma Inc. is a biopharmaceutical company focused on the development of therapeutic applications for botulinum toxin. The company aims to advance treatments for a range of medical conditions, particularly in neurology and related therapeutic areas. AEON Biopharma is engaged in clinical research and regulatory processes to expand the use of botulinum toxin beyond aesthetic applications. The company is headquartered in Irvine, California, and its shares are listed on the NYSE.

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