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Agomab Therapeutics (AGMB) investor relations material
Agomab Therapeutics Registration Filing summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Company overview and business model
Clinical-stage biopharmaceutical company developing disease-modifying therapies for immunology and inflammatory diseases, focusing initially on chronic fibrotic indications with high unmet medical need.
Lead product candidates: ontunisertib (oral, GI-restricted ALK5 inhibitor for fibrostenosing Crohn's disease) and AGMB-447 (inhaled ALK5 inhibitor for idiopathic pulmonary fibrosis).
Pipeline includes preclinical programs, notably AGMB-101, an HGF-mimetic monoclonal antibody for liver cirrhosis.
Retains exclusive, worldwide development and commercialization rights to all product candidates.
Strategy leverages established biological pathways and validated modalities to increase efficacy and minimize systemic toxicity.
Financial performance and metrics
No product revenue to date; operations funded by €299.7 million in equity from strategic and institutional investors.
Net losses: €46.3 million (2024), €11.4 million (2023); accumulated loss of €164.3 million as of September 30, 2025.
R&D expenses: €39.3 million (2024), €26.3 million (2023); G&A expenses: €10.1 million (2024), €6.1 million (2023).
Cash and cash equivalents: €129.6 million as of September 30, 2025.
Operating cash outflows: €38.6 million for the nine months ended September 30, 2025.
Use of proceeds and capital allocation
Net proceeds from the IPO, together with existing cash, will fund clinical development of ontunisertib (Phase 2b in FSCD) and AGMB-447 (Phase 2 in IPF), advancement of preclinical candidates, milestone payment for Origo Biopharma acquisition, G&A expenses, and working capital.
Management retains broad discretion over allocation of net proceeds.
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