Agomab Therapeutics
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Agomab Therapeutics (AGMB) investor relations material

Agomab Therapeutics has been private

Agomab Therapeutics Registration Filing summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Registration Filing summary16 Jan, 2026

Company overview and business model

  • Clinical-stage biopharmaceutical company developing disease-modifying therapies for immunology and inflammatory diseases, focusing initially on chronic fibrotic indications with high unmet medical need.

  • Lead product candidates: ontunisertib (oral, GI-restricted ALK5 inhibitor for fibrostenosing Crohn's disease) and AGMB-447 (inhaled ALK5 inhibitor for idiopathic pulmonary fibrosis).

  • Pipeline includes preclinical programs, notably AGMB-101, an HGF-mimetic monoclonal antibody for liver cirrhosis.

  • Retains exclusive, worldwide development and commercialization rights to all product candidates.

  • Strategy leverages established biological pathways and validated modalities to increase efficacy and minimize systemic toxicity.

Financial performance and metrics

  • No product revenue to date; operations funded by €299.7 million in equity from strategic and institutional investors.

  • Net losses: €46.3 million (2024), €11.4 million (2023); accumulated loss of €164.3 million as of September 30, 2025.

  • R&D expenses: €39.3 million (2024), €26.3 million (2023); G&A expenses: €10.1 million (2024), €6.1 million (2023).

  • Cash and cash equivalents: €129.6 million as of September 30, 2025.

  • Operating cash outflows: €38.6 million for the nine months ended September 30, 2025.

Use of proceeds and capital allocation

  • Net proceeds from the IPO, together with existing cash, will fund clinical development of ontunisertib (Phase 2b in FSCD) and AGMB-447 (Phase 2 in IPF), advancement of preclinical candidates, milestone payment for Origo Biopharma acquisition, G&A expenses, and working capital.

  • Management retains broad discretion over allocation of net proceeds.

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