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Akari Therapeutics (AKTX) investor relations material
Akari Therapeutics Q2 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
Executive summary
Focus shifted to next-generation antibody-drug conjugates (ADCs) after the Peak Bio merger, with legacy programs suspended or seeking external partners.
Lead candidate AKTX-101 targets Trop2 in solid tumors, leveraging a novel PH1 payload for improved efficacy and immune activation.
Significant operational restructuring in May 2024, including a 67% workforce reduction and management changes, to align with new R&D priorities.
No commercial products or product revenue to date; ongoing reliance on external financing.
Financial highlights
Net loss for Q2 2025 was $1.9 million, a 75% improvement year-over-year; six-month net loss was $5.6 million, down 57% from prior year.
Operating expenses for Q2 2025 decreased 58% to $3.1 million, driven by lower R&D and absence of merger/restructuring costs.
Cash and restricted cash at June 30, 2025 totaled $2.7 million; accumulated deficit reached $252.9 million.
Recognized a $1.2 million gain on settlement of current liabilities in Q2 2025.
No revenue generated; all expenses relate to R&D and G&A.
Outlook and guidance
Cash and committed funds expected to fund operations into October 2025; additional capital will be required to continue beyond that point.
Management is actively pursuing further financing, including equity, debt, and strategic partnerships.
Substantial doubt exists regarding ability to continue as a going concern without new funding.
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