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Akebia Therapeutics (AKBA) investor relations material
Akebia Therapeutics H.C. Wainwright 27th Annual Global Investment Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
Commercial performance and product focus
Vafseo generated over $13 million in Q2 revenue with 55% demand growth, driven by both breadth and depth of prescribing, including 725 prescribers and strong penetration in US Renal Care clinics.
Auryxia, despite loss of IP exclusivity, achieved 15% year-over-year growth and continues to contribute to revenue, supported by favorable economics and clinical profile.
Vafseo's dosing in real-world use aligns with clinical trial data, with 80% of Q2 prescriptions being refills and average doses increasing over time.
Expansion into dialysis organizations and market opportunity
Innovative Renal Care and Dialysis Clinic Inc. have operationalized protocols, providing access to 32,000 patients, with DaVita's pilot potentially opening access to 204,000 patients by year-end.
The total addressable market includes 550,000 anemic CKD patients on dialysis, with ongoing efforts to engage Fresenius for future access, targeting P&T committee review in 2026.
Clinical development and future growth drivers
The VACE trial aims to demonstrate reductions in hospitalization and mortality, supporting Vafseo's case as a standard of care and offering significant economic benefits to dialysis organizations.
The Phase 3 VALOR trial for non-dialysis CKD patients is planned to start by year-end, targeting a similarly sized patient population and representing a multi-billion dollar opportunity.
Broad usage of Vafseo has been observed, not limited to home or high-dose ESA patients, indicating strong market acceptance.
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