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Aligos Therapeutics (ALGS) investor relations material
Aligos Therapeutics H.C. Wainwright Liver Disease Virtual Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.H.C. Wainwright Liver Disease Virtual Conference summary21 Oct, 2025
Conference overview
The event combined viral hepatitis, MASH, and liver cancer topics, featuring leading biotech companies and key opinion leaders.
Focus was on innovative therapies for HBV, HDV, MASH, and liver cancer.
HBV disease landscape and unmet need
HBV is the most prevalent chronic viral infection, leading to significant morbidity and mortality.
Current nucleoside/nucleotide analogs suppress viral replication but do not eliminate cccDNA, leaving risk for disease progression.
Deep and rapid viral suppression is linked to better patient outcomes and reduced risk of liver cancer.
Pevifoscorvir (pevi) program highlights
Pevi is a next-generation capsid assembly modulator, chemically optimized for potency and bioavailability.
Demonstrates dual mechanisms: blocks encapsulation of pre-genomic RNA and inhibits cccDNA establishment.
Only capsid assembly modulator shown to reduce antigens and cccDNA in clinical and cell culture studies.
96-week data show durable viral suppression and multi-antigen reductions, outperforming traditional therapies.
No resistance observed in monotherapy, even in patients with baseline resistant variants.
What enables Pevi's monotherapy regulatory path?
Pevi's role in functional cure combination therapy?
ALG-055009 partnering: structure and timing?
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Next Aligos Therapeutics earnings date
Q3 20256 Nov, 2025
Next Aligos Therapeutics earnings date
Q3 20256 Nov, 2025
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Frequently asked questions
Aligos Therapeutics Inc. is a clinical-stage biopharmaceutical company engaged in the development of novel therapeutics to address unmet medical needs in viral and liver diseases. The company's development pipeline includes drug candidates for the treatment of conditions such as non-alcoholic steatohepatitis (NASH), chronic hepatitis B (CHB), and coronavirus. Aligos Therapeutics utilizes a combination of small molecule and oligonucleotide platforms to create pharmacologically optimized drug candidates aimed at improving treatment outcomes in these diseases. The company is headquartered in South San Francisco, California, and its shares are listed on the Nasdaq.
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