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Alvotech (ALVO) investor relations material
Alvotech Jefferies London Healthcare Conference 2025 summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Strategic positioning and partnerships
Operates in over 90 countries with 20 commercial partners, leveraging a global partnership model to access regional market leaders.
Invested $2 billion in a state-of-the-art manufacturing facility in Reykjavík, with additional R&D and packaging acquisitions in Sweden and Switzerland to improve cost structure and lead times.
Transitioning from 2 to 4–6 programs annually, supported by in-house R&D and manufacturing integration.
Key partners include Teva (U.S.), JAMP (Canada), STADA and Advanz (Europe), and Dr. Reddy's (Europe/U.S.).
Product portfolio and market growth
Currently markets biosimilar Humira (Simlandi) and Stelara, with Simlandi becoming the second largest biosimilar in the U.S. by market share.
U.S. biosimilar Humira market has reached 50% conversion since 2023, with further volume growth expected.
Stelara biosimilar launched in Q2, with 25% market conversion expected to grow to 50–70% in coming years.
Four new products (Prolex, Jiva, Symphony, Eylea) are set for launch, expanding the portfolio from two to six products.
Eylea and Symphony have approvals in Japan, U.K., and Europe, with U.S. launches planned for 2025–2026.
Regulatory and operational updates
Recent U.K. court win against Regeneron supports Eylea launch; Symphony received positive EMA CHMP opinion and is expected to launch in Japan (H1 2026), Europe (this quarter), and U.S. (next year).
FDA issued a CRL for Symphony due to facility observations, not product deficiencies; 95% of remediation is complete, and the facility remains approved for other products.
Confident in resolving FDA queries and maintaining the roadmap to be first to market with Symphony in the U.S.
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