Ardelyx
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Ardelyx (ARDX) investor relations material

Ardelyx Q3 2026 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2026 earnings summary3 Nov, 2026

Executive summary

  • Q3 product revenue was $125.5M, up 19% YoY; total revenue was $127.7M, up 16% YoY.

  • Net loss narrowed to $0.7M; cash, cash equivalents and short-term investments totaled $285.3M at September 30, 2026.

  • Priorities include accelerating IBSRELA, sustaining XPHOZAH momentum, advancing the pipeline and maintaining financial flexibility.

Financial highlights

  • Total product revenue was $125.5M vs. $105.5M in Q3 2025; total revenue was $127.7M vs. $110.3M.

  • Q3 net loss was $0.7M vs. $1.0M; operating income was $4.0M vs. $4.7M.

  • R&D expense was $25.2M vs. $18.1M; SG&A was $93.9M vs. $83.6M, reflecting pipeline and commercial investment.

  • 9M revenue was $343.0M vs. $282.1M; net loss narrowed to $55.1M from $61.2M.

Outlook and guidance

  • Reaffirmed FY 2026 IBSRELA revenue guidance of $350M–$370M and XPHOZAH guidance of $110M–$120M; operating expenses expected below $500M.

  • IBSRELA guidance implies annual growth above 30% at the midpoint; long-term annual U.S. revenue target remains $1B.

  • Profitability remains targeted for 2027; ACCEL CIC Phase 3 topline results expected in H2 2027.

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Jefferies Global Healthcare Conference17 Nov, 2026
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Frequently asked questions

Ardelyx Inc is a biopharmaceutical company engaged in discovering, developing, and commercializing novel treatments for patients with gastrointestinal and cardiorenal diseases. Their approach focuses on creating targeted, first-in-class, oral, small molecule therapies that address significant unmet medical needs. The company's flagship product candidate is tenapanor, aimed at treating irritable bowel syndrome with constipation. Furthermore, Ardelyx is advancing XPHOZAH in Phase III clinical trials for controlling serum phosphorus in patients with chronic kidney disease on dialysis, and other product candidates like RDX013 and RDX020 target hyperkalemia and metabolic acidosis, respectively. Ardelyx has formed strategic partnerships with Kyowa Kirin, Fosun Pharmaceutical Industrial Development Co. Ltd., and Knight Therapeutics, Inc. for the development and commercialization of tenapanor in various territories. Originally founded as Nteryx, Inc., the company rebranded to Ardelyx, Inc. in 2008 and is headquartered in Waltham, Massachusetts, with its shares listed on the NASDAQ.