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Arovella Therapeutics (ALA) investor relations material
Arovella Therapeutics Q2 2026 TU earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Filed IND application for ALA-101 with the U.S. FDA, advancing toward first-in-human Phase 1 trial for CD19-positive lymphoma and leukemia.
Selected SAPRO as CRO for the Phase 1 trial, with trial start-up activities underway and expected commencement in early 2026.
Demonstrated potent in vitro activity of CLDN18.2-targeting CAR for ALA-105 program, supporting expansion into solid tumors.
Exercised option to in-license additional CAR targets and iNKT-related technology from Baylor College of Medicine.
Appointed Dr Andrew Nash as Non-Executive Director, with intention to transition to Non-Executive Chairman.
Financial highlights
Cash and cash equivalents at 31 December 2025 totaled $19.4 million.
Quarterly cash outflows from operating activities were $2.5 million, with R&D and staff costs comprising 90% of outflows.
Payments to related parties for the quarter were $154,063, covering director fees and executive salaries.
Estimated 7.6 quarters of funding available based on current cash burn.
Outlook and guidance
Phase 1 clinical trial for ALA-101 expected to commence early 2026, with funding secured to complete enrollment and report initial safety and efficacy data.
Continued progress anticipated in solid tumor program targeting CLDN18.2 and integration of IL-12-TM armouring technology.
Ongoing review of new technologies for potential acquisition to enhance or expand the CAR-iNKT cell platform.
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