Arovella Therapeutics
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Arovella Therapeutics (ALA) investor relations material

Arovella Therapeutics Q2 2026 TU earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q2 2026 TU earnings summary22 Jan, 2026

Executive summary

  • Filed IND application for ALA-101 with the U.S. FDA, advancing toward first-in-human Phase 1 trial for CD19-positive lymphoma and leukemia.

  • Selected SAPRO as CRO for the Phase 1 trial, with trial start-up activities underway and expected commencement in early 2026.

  • Demonstrated potent in vitro activity of CLDN18.2-targeting CAR for ALA-105 program, supporting expansion into solid tumors.

  • Exercised option to in-license additional CAR targets and iNKT-related technology from Baylor College of Medicine.

  • Appointed Dr Andrew Nash as Non-Executive Director, with intention to transition to Non-Executive Chairman.

Financial highlights

  • Cash and cash equivalents at 31 December 2025 totaled $19.4 million.

  • Quarterly cash outflows from operating activities were $2.5 million, with R&D and staff costs comprising 90% of outflows.

  • Payments to related parties for the quarter were $154,063, covering director fees and executive salaries.

  • Estimated 7.6 quarters of funding available based on current cash burn.

Outlook and guidance

  • Phase 1 clinical trial for ALA-101 expected to commence early 2026, with funding secured to complete enrollment and report initial safety and efficacy data.

  • Continued progress anticipated in solid tumor program targeting CLDN18.2 and integration of IL-12-TM armouring technology.

  • Ongoing review of new technologies for potential acquisition to enhance or expand the CAR-iNKT cell platform.

ALA-101 trial start date and key milestones
CLDN18.2 CAR-iNKT in vivo study plans
Baylor DLA progress and new CAR strategic impact
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H1 202626 Feb, 2026
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Frequently asked questions

Arovella Therapeutics Limited is a biotechnology company specializing in the development of innovative therapies for cancer and other conditions affecting the central nervous system. The company focuses on advancing its proprietary technology platforms to create novel immunotherapies and treatments that target specific disease mechanisms. Arovella's research emphasizes the development of therapies that harness the body's immune system to combat cancer, as well as drug delivery systems to enhance the effectiveness of pharmaceutical compounds. Arovella Therapeutics Limited is headquartered in Sydney, Australia, and its shares are listed on the ASX.

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