Artelo Biosciences
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Artelo Biosciences (ARTL) investor relations material

Artelo Biosciences Q4 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q4 2025 earnings summary24 Feb, 2026

Executive summary

  • Achieved positive first-in-human Phase 1 data for ART26.12, showing favorable safety and pharmacokinetics, with preparations underway for a multiple ascending dose study in Q3 2026.

  • Interim Phase 2 CARES data for ART27.13 demonstrated improvements in body weight, lean body mass, and physical activity in cancer anorexia-cachexia patients, with a favorable side-effect profile.

  • Received favorable UK MHRA regulatory guidance for ART12.11, supporting Phase 1 study plans and potential accelerated pathways, with human studies planned for early 2027.

  • Secured a Notice of Allowance from the European Patent Office for ART27.13, extending patent protection through December 2041.

Financial highlights

  • Research and development expenses were $5.4 million for 2025, down from $6.0 million in 2024.

  • General and administrative expenses increased to $6.0 million in 2025 from $4.1 million in 2024.

  • Net loss for 2025 was $12.9 million, or $12.52 per share, compared to $9.8 million in 2024.

  • Cash and investments totaled $0.6 million as of December 31, 2025.

Outlook and guidance

  • Multiple ascending dose study for ART26.12 expected to begin enrollment in Q3 2026.

  • Human clinical studies for ART12.11 planned for the first half of 2027, pending toxicology results.

  • Focus remains on disciplined clinical execution, strategic collaboration, and prudent capital management.

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Frequently asked questions

Artelo Biosciences Inc. is a clinical-stage biopharmaceutical company focused on the development and commercialization of proprietary therapeutics. These therapeutics are designed to modulate lipid-signaling pathways, including the endocannabinoid system, aiming to address significant unmet medical needs across various diseases and conditions such as anorexia, cancer, anxiety, pain, neuropathy, and inflammation. Artelo is advancing a diverse portfolio of product candidates, including ART27.13, a synthetic dual cannabinoid G protein-coupled receptor agonist for treating anorexia associated with cancer; ART12.11, a synthetic cannabidiol cocrystal targeting inflammatory bowel disease and post-traumatic stress disorder (PTSD); and ART26.12, a fatty acid binding protein 5 inhibitor intended for breast and prostate cancer, neuropathic and nociceptive pain, and anxiety disorders, including PTSD. The company is headquartered in Solana Beach, California, and its shares are listed on the Nasdaq.

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