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Arvinas (ARVN) investor relations material
Arvinas Q3 2026 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Portfolio strategy prioritizes programs with the strongest emerging evidence of potential value; multiple clinical data milestones are expected through 2027.
Clinical portfolio includes ARV-393 for lymphoma, ARV-027 for SBMA, ARV-6723 for cancer immunotherapy and ARV-102 for neurodegenerative disease.
VEPPANU was launched in the U.S. by Rigel on August 13, 2026, following FDA approval in Q2 2026.
Financial highlights
Q3 revenue was $0.5M vs. $41.9M YoY; 9M revenue was $265.8M vs. $253.1M, including collaboration and licensing revenue and a $50.0M VEPPANU approval milestone.
Q3 net loss was $53.9M vs. $35.1M; 9M net income was $57.9M vs. a $13.4M net loss.
Q3 R&D was $46.9M and G&A was $12.6M, down from $64.7M and $21.0M YoY; non-GAAP quarterly expenses declined 25% YoY to $53.5M.
Q3 included $0.5M in Rigel license royalties; the related Yale royalty was recorded in cost of license revenue.
Outlook and guidance
ARV-393 early monotherapy data, including safety, PK, PD and preliminary efficacy, are targeted for Q4 2026; additional monotherapy and glofitamab-combination data are planned for mid-2027.
ARV-027 healthy-volunteer Phase 1 data and SBMA patient dosing are expected in H1 2027; ARV-6723 pembrolizumab-combination dosing is planned for mid-2027, with initial monotherapy data in H2 2027.
ARV-102 PSP Phase 1b trial initiation in the EU and UK is targeted for 2027, pending CTA submissions and authorization; EU CTA planned for Q4 2026 and UK CTA for Q1 2027.
Quarterly spend is expected to remain similar over the next few quarters; R&D expenses are expected to increase substantially as clinical trials advance.
- Four clinical programs approach key milestones, with cash guidance into 2H 2028.ARVN
Wells Fargo 21st Annual Healthcare Conference - Four phase I programs advance toward major data readouts, backed by strong capital and strategic focus.ARVN
Morgan Stanley 24th Annual Global Healthcare Conference - Multiple clinical programs advance toward key data readouts, supported by strong capital and science.ARVN
12th Annual Cantor Fitzgerald Global Healthcare Conference - FDA approval and out-licensing of VEPPANU drove record Q2 revenue and net income.ARVN
Q2 2026 - Phase III vepdegestrant data and new combination results are set to drive multiple launches and pipeline growth.ARVN
2024 Cantor Fitzgerald Global Healthcare Conference - All voting items passed at the virtual meeting, with no shareholder questions submitted.ARVN
AGM 2026 - First PROTAC approval, focused pipeline, and key clinical milestones ahead in PSP and SBMA.ARVN
Jefferies Global Healthcare Conference 2026 - Vepdegestrant improved median PFS by 2.9 months over fulvestrant in ESR1-mutant breast cancer.ARVN
Study Update - Q1 2025 saw revenue and net income surge, with restructuring extending cash runway into 2H 2028.ARVN
Q1 2025
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