Arvinas
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Arvinas (ARVN) investor relations material

Arvinas Q3 2026 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2026 earnings summary3 Nov, 2026

Executive summary

  • Portfolio strategy prioritizes programs with the strongest emerging evidence of potential value; multiple clinical data milestones are expected through 2027.

  • Clinical portfolio includes ARV-393 for lymphoma, ARV-027 for SBMA, ARV-6723 for cancer immunotherapy and ARV-102 for neurodegenerative disease.

  • VEPPANU was launched in the U.S. by Rigel on August 13, 2026, following FDA approval in Q2 2026.

Financial highlights

  • Q3 revenue was $0.5M vs. $41.9M YoY; 9M revenue was $265.8M vs. $253.1M, including collaboration and licensing revenue and a $50.0M VEPPANU approval milestone.

  • Q3 net loss was $53.9M vs. $35.1M; 9M net income was $57.9M vs. a $13.4M net loss.

  • Q3 R&D was $46.9M and G&A was $12.6M, down from $64.7M and $21.0M YoY; non-GAAP quarterly expenses declined 25% YoY to $53.5M.

  • Q3 included $0.5M in Rigel license royalties; the related Yale royalty was recorded in cost of license revenue.

Outlook and guidance

  • ARV-393 early monotherapy data, including safety, PK, PD and preliminary efficacy, are targeted for Q4 2026; additional monotherapy and glofitamab-combination data are planned for mid-2027.

  • ARV-027 healthy-volunteer Phase 1 data and SBMA patient dosing are expected in H1 2027; ARV-6723 pembrolizumab-combination dosing is planned for mid-2027, with initial monotherapy data in H2 2027.

  • ARV-102 PSP Phase 1b trial initiation in the EU and UK is targeted for 2027, pending CTA submissions and authorization; EU CTA planned for Q4 2026 and UK CTA for Q1 2027.

  • Quarterly spend is expected to remain similar over the next few quarters; R&D expenses are expected to increase substantially as clinical trials advance.

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Frequently asked questions

Arvinas Inc is a clinical-stage biopharmaceutical company focused on the development of novel therapeutics for the treatment of cancer and other diseases. Utilizing its proprietary PROTAC® (Proteolysis Targeting Chimera) technology, Arvinas aims to degrade disease-causing proteins, which is a novel approach in the field of drug development. This technology harnesses the body's natural protein disposal system to selectively and efficiently remove aberrant proteins. The company's pipeline includes therapies targeting a range of diseases with significant unmet medical need, emphasizing oncology and neuroscience. The company is headquartered in New Haven, Connecticut, and its shares are listed on the NASDAQ.