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Assembly Biosciences (ASMB) investor relations material
Assembly Biosciences Q2 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q2 2025 earnings summary6 Aug, 2025
Executive summary
Focused on developing therapeutics for serious viral diseases, advancing four clinical candidates in 2025, and collaborating with Gilead Sciences.
Pipeline includes helicase-primase inhibitors for genital herpes, an HDV entry inhibitor, a next-gen HBV capsid modulator, and a broad-spectrum NNPI for transplant-related herpesviruses.
Reported positive interim and topline results for several Phase 1 studies, including hepatitis and herpes programs.
Presented new clinical and preclinical data at major scientific conferences, highlighting HSV and HBV/HDV progress.
Gilead collaboration provides funding, opt-in rights, milestone/royalty payments, and increased equity stake.
Financial highlights
Collaboration revenue was $9.6M for Q2 2025, up 13% year-over-year; $19.0M for the six months, up 33%.
Cash, cash equivalents, and marketable securities totaled $75.0M as of June 30, 2025, down from $91.0M at March 31, 2025.
Net loss for Q2 2025 was $10.2M ($1.33/share), improved from $11.2M ($1.98/share) in Q2 2024.
Research and development expenses for Q2 2025 were $16.1M, slightly down year-over-year due to lower ABI-6250 costs.
Operating cash outflow was $40.2M for the first half of 2025, up from $35.5M in the prior year.
Outlook and guidance
Cash runway projected to fund operations into mid-2026; substantial doubt exists about ability to continue beyond that without new funding.
Plans to seek further funding through equity or collaboration payments; future capital needs depend on pipeline progress and Gilead outcomes.
Proof-of-concept Phase 1b data for ABI-5366 and ABI-1179 in genital herpes expected by fall 2025.
ABI-6250 preclinical data to be presented at the International HBV Meeting in September 2025.
Next major HSV program milestone?
What caused collaboration revenue increase?
What did ABI-6250 biomarker data indicate?
Partial view of Summaries dataset, powered by Quartr API
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Next Assembly Biosciences earnings date
Q3 20257 Nov, 2025
Next Assembly Biosciences earnings date
Q3 20257 Nov, 2025
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Frequently asked questions
Assembly Biosciences, Inc. is a biopharmaceutical company focused on developing small molecule antiviral therapeutics. It is primarily engaged in the discovery and development of treatments targeting hepatitis B virus (HBV) and hepatitis delta virus (HDV), including a portfolio of HBV core inhibitors and other novel antiviral compounds aimed at managing chronic infections. Additionally, the company explores therapies for herpesviruses, with programs advancing long-acting inhibitors and other non-nucleoside polymerase inhibitors intended for transplant-associated infections and other serious disease conditions. Assembly Biosciences is headquartered in South San Francisco, California, and its shares are listed on the NASDAQ.
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