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Aurinia Pharmaceuticals (AUPH) investor relations material
Aurinia Pharmaceuticals Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
LUPKYNIS sales grew 25% year-over-year in 2025, reaching $271.3 million, with strong commercial momentum and robust patient growth.
Total revenue for 2025 was $283.1 million, up 20% from 2024, primarily driven by LUPKYNIS sales.
Net income for 2025 surged to $287.2 million, up 4,852% year-over-year, mainly due to a significant income tax benefit from the release of a valuation allowance on deferred tax assets.
Advanced aritinercept clinical development, initiating studies in autoimmune diseases and planning further trials in 2026.
Terminated VOCAL pediatric studies due to recruitment challenges, with plans to discuss pediatric commitments with the FDA.
Financial highlights
Q4 2025 total revenue was $77.1 million, up 29% year-over-year; net product sales of LUPKYNIS were $74.2 million, up 29%.
Full-year 2025 net product sales were $271.3 million, up 25% year-over-year.
License, collaboration, and royalty revenue for 2025 was $11.7 million, down 38% due to a prior year milestone payment.
Q4 2025 net income was $210.8 million, up 14,957% year-over-year, driven by a $175.1 million income tax benefit.
Full-year 2025 net income before taxes was $114.2 million, up 1,443% year-over-year.
Outlook and guidance
2026 total revenue guidance is $315 million–$325 million, up 11%–15% from 2025.
2026 net product sales guidance for LUPKYNIS is $305 million–$315 million, up 12%–16% year-over-year.
Guidance incorporates new competition, guideline implementation, and historical growth trends.
Focus remains on increasing LUPKYNIS adoption and advancing aritinercept clinical programs.
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