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Aurinia Pharmaceuticals (AUPH) investor relations material

Aurinia Pharmaceuticals Q3 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2025 earnings summary4 Nov, 2025

Executive summary

  • LUPKYNIS sales grew 27% year-over-year in Q3 2025, driven by strong demand, updated treatment guidelines, and increased prescriber adoption.

  • Net product sales for the nine months ended September 30, 2025, increased 24% year-over-year, with total revenue up 17% to $205.9M.

  • Net income surged 119% in Q3 and 1,677% for the nine months, with diluted EPS up 130% in Q3 and 1,733% for the nine months.

  • Aritinercept, a dual BAFF/APRIL inhibitor, advanced toward clinical studies in two autoimmune diseases, with positive Phase 1 results and further details expected in early 2026.

  • Strategic restructuring in 2024 reduced headcount by approximately 70% and discontinued the AUR300 program, focusing resources on LUPKYNIS and aritinercept.

Financial highlights

  • Q3 2025 total revenue: $73.5M, up 8% from Q3 2024; nine months: $205.9M, up 17% year-over-year.

  • LUPKYNIS net product sales: $70.6M in Q3 (up 27% YoY); $197.2M for nine months (up 24% YoY).

  • Q3 2025 net income: $31.6M, up 119% YoY; nine months: $76.4M, up 1,677% YoY.

  • Cash flows from operating activities: $44.5M in Q3 (up 162%), $90M for nine months (up 529%).

  • Cash, equivalents, and investments: $351.8M as of September 30, 2025.

Outlook and guidance

  • 2025 total revenue guidance raised to $275M–$280M; net product sales guidance raised to $265M–$270M.

  • LUPKYNIS expected to maintain positive momentum into Q4 and 2026, supported by updated treatment guidelines.

  • Clinical studies for aritinercept in two autoimmune diseases planned by year-end 2025, with more details in early 2026.

  • SG&A expenses expected to remain lower in 2025 due to restructuring, while R&D expenses are projected to increase.

  • The company expects to fund future operations with existing cash or future operating cash flows.

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Frequently asked questions

Aurinia is a biopharmaceutical company driven by a relentless commitment to bring life-changing therapies, like voclosporin, to patients suffering from diseases with high unmet medical need. The Company’s lead product, voclosporin, is being investigated as a therapy for LN. The Company is initially targeting LN and has plans to study additional disease indications. The company is headquartered in Victoria, Canada.

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