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Avacta Group (AVCT) investor relations material
Avacta Group H1 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.H1 2025 earnings summary30 Sep, 2025
Executive summary
Clinical programs are advancing, with ongoing Phase 1b expansion cohorts for AVA6000 (faridoxorubicin) showing encouraging initial activity and pivotal data expected at ESMO 2025 and late 2025.
AVA6103 (FAP-EXD) remains on track for first patient dosing in Q1 2026, with strong preclinical data showing durable responses in resistant animal models.
Strategic focus on partnerships, business development, and collaborations, including with Tempus AI, to support funding and clinical advancement.
Industry interest in the pre|CISION platform is increasing, with a pipeline update planned for October and new applications to be showcased.
Sale of Launch Diagnostics and Coris Diagnostics completed, supporting cash position.
Financial highlights
Cash and cash equivalents at period end were £12.65 million, down from £28.56 million year-over-year and £12.87 million at 2024 year-end.
Cash outflows from operations and working capital were £12.14 million for 1H25, compared to £12.6 million in 1H24.
Cash inflows from investing activities were £8.77 million, mainly from the sale of Launch Diagnostics.
Revenue from continuing operations was £0.06 million, unchanged year-over-year; discontinued operations revenue was £6.10 million.
Operating loss from continuing operations decreased to £14.18 million (H1 2024: £14.86 million).
Outlook and guidance
Cash runway extends into Q1 2026, with ongoing focus on strategic partnerships and funding levers.
Multiple pipeline updates and key data catalysts expected in late 2025, including ESMO 2025, salivary gland data, and initial AVA6103 clinical data in late 2026.
No further development of AVA6000 Phase 2 will occur without a partnership; maturing Phase 1B data expected to drive inflection points.
Impact of maturing Phase Ib data on partnerships
Rationale for 100% FAP-exatecan ownership?
Explain the new pre|CISION platform leverage.
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Next Avacta Group earnings date
AGM 202529 Oct, 2025
Next Avacta Group earnings date
AGM 202529 Oct, 2025
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Frequently asked questions
Avacta Group PLC is a biotechnology company specializing in the development of innovative diagnostic and therapeutic solutions. The company operates in two primary segments: diagnostics, where it develops rapid tests and reagents, and therapeutics, focusing on the development of precision oncology treatments. Avacta utilizes proprietary technologies, such as its Affimer platform, to create targeted therapies and diagnostic tools. The company is headquartered in Wetherby, United Kingdom, and its shares are listed on the AIM.
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