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Aytu Biopharma (AYTU) investor relations material

Aytu Biopharma Planet MicroCap Showcase: TORONTO 2025 summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Planet MicroCap Showcase: TORONTO 2025 summary22 Oct, 2025

Strategic transformation and business focus

  • Shifted to a pure-play CNS specialty pharma, divesting non-core assets and consumer health business since 2022.

  • Outsourced manufacturing, reorganized headcount, and improved adjusted EBITDA by $35 million.

  • Paid off and refinanced term loan, cleaned up balance sheet, and now sits on $31 million cash.

  • Core ADHD products generate $58 million of $66 million total revenue, with stable gross margins around 69%.

  • Out-licensed ADHD products in Israel and Canada, with future revenue expected.

Product portfolio and market positioning

  • ADHD portfolio includes Adzenys, Cotempla, and recently launched Metadate CD, with strong prescription growth due to U.S. Adderall shortages.

  • RxConnect patient access program ensures affordable prescriptions and high refill rates, with 85% of scripts through 1,000+ contracted pharmacies.

  • Sales force of 40 reps targets psychiatrists and GPs, with 60% overlap for new MDD product Exxua.

  • ADHD market share is about 0.6%, but business is stable and cash flow neutral.

Exxua (Gepirone) launch and opportunity

  • Licensed Exxua for MDD, approved in September 2023, launching December 2024, with patent protection through 2030 and plans for extension.

  • Exxua targets a $22 billion MDD market, with 340 million annual prescriptions, and is positioned as a third- or fourth-line therapy.

  • Key differentiator: no sexual dysfunction or weight change side effects, unlike SSRIs/SNRIs.

  • Clinical trials showed efficacy by week three, with transient dizziness and nausea as main side effects.

  • Market research: 39 of 40 surveyed psychiatrists would prescribe Exxua; strong psychiatrist interest in side effect profile.

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Next Aytu Biopharma earnings date

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Q1 202612 Nov, 2025
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Frequently asked questions

Aytu Biopharma Inc is a specialty pharmaceutical company focused on developing and commercializing treatments for rare and pediatric-onset disorders. The company’s portfolio includes prescription therapeutics and consumer health products targeting genetic, neurological, and respiratory conditions. It operates through research, licensing, and marketing of branded pharmaceuticals. Aytu Biopharma Inc is headquartered in Englewood, Colorado, and its shares are listed on the NASDAQ.

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