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Aytu Biopharma (AYTU) investor relations material

Aytu Biopharma Lytham Partners Fall 2025 Investor Conference summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Lytham Partners Fall 2025 Investor Conference summary30 Sep, 2025

Strategic realignment and financial performance

  • Refocused on core prescription business, exiting unprofitable segments and in-house manufacturing by end of 2024.

  • Divested consumer health business by mid-2025, improving profitability and margins.

  • Achieved consistent positive adjusted EBITDA of $9–10 million over the past three years.

  • Maintains a solid revenue base with over $66 million in trailing 12-month net revenues.

  • Ended June 2025 with over $30 million in cash and manageable debt refinanced to 2029.

Product portfolio and upcoming launch

  • Core focus on CNS brands, especially ADHD medications Adzenys XR-ODT and COTEMPLA XR-ODT.

  • Preparing to launch Exxua, a novel antidepressant for major depressive disorder, in Q4 2025.

  • Exxua is FDA approved, weight neutral, and does not cause sexual dysfunction, differentiating it from SSRIs/SNRIs.

  • Exxua targets the 5-HT1A receptor, offering a unique mechanism of action.

  • Patent protection for Exxua extends through late 2030, with plans for lifecycle extension.

Commercial infrastructure and market opportunity

  • 40-person sales force already established in psychiatry, covering 60% of major depressive disorder prescribers.

  • Exxua will become the primary focus, leveraging existing relationships with psychiatrists.

  • The depression market exceeds 340 million annual prescriptions and $22 billion in value.

  • Exxua will be priced at a premium, with favorable reimbursement expected from Medicaid and Medicare.

  • Recent capital raise and stable base business will fund Exxua’s launch and promotional activities.

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Frequently asked questions

Aytu Biopharma Inc is a specialty pharmaceutical company focused on developing and commercializing treatments for rare and pediatric-onset disorders. The company’s portfolio includes prescription therapeutics and consumer health products targeting genetic, neurological, and respiratory conditions. It operates through research, licensing, and marketing of branded pharmaceuticals. Aytu Biopharma Inc is headquartered in Englewood, Colorado, and its shares are listed on the NASDAQ.

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