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Aytu Biopharma (AYTU) investor relations material
Aytu Biopharma Lytham Partners Fall 2025 Investor Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
Strategic realignment and financial performance
Refocused on core prescription business, exiting unprofitable segments and in-house manufacturing by end of 2024.
Divested consumer health business by mid-2025, improving profitability and margins.
Achieved consistent positive adjusted EBITDA of $9–10 million over the past three years.
Maintains a solid revenue base with over $66 million in trailing 12-month net revenues.
Ended June 2025 with over $30 million in cash and manageable debt refinanced to 2029.
Product portfolio and upcoming launch
Core focus on CNS brands, especially ADHD medications Adzenys XR-ODT and COTEMPLA XR-ODT.
Preparing to launch Exxua, a novel antidepressant for major depressive disorder, in Q4 2025.
Exxua is FDA approved, weight neutral, and does not cause sexual dysfunction, differentiating it from SSRIs/SNRIs.
Exxua targets the 5-HT1A receptor, offering a unique mechanism of action.
Patent protection for Exxua extends through late 2030, with plans for lifecycle extension.
Commercial infrastructure and market opportunity
40-person sales force already established in psychiatry, covering 60% of major depressive disorder prescribers.
Exxua will become the primary focus, leveraging existing relationships with psychiatrists.
The depression market exceeds 340 million annual prescriptions and $22 billion in value.
Exxua will be priced at a premium, with favorable reimbursement expected from Medicaid and Medicare.
Recent capital raise and stable base business will fund Exxua’s launch and promotional activities.
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