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Basilea Pharmaceutica (BSLN) investor relations material

Basilea Pharmaceutica H1 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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H1 2025 earnings summary19 Aug, 2025

Executive summary

  • Achieved 36.3% year-over-year revenue growth to CHF104M in H1 2025, with a 24.8% increase in Cresemba global in-market sales and 21.7% higher royalty income.

  • Launched Zevtera in the US, expanding commercial reach and addressing high unmet medical needs in severe infections.

  • Advanced pipeline with a second Phase III study for fosmanogepix and in-licensed ceftibuten-ledobarbactam, a Phase III-ready oral antibiotic for complicated UTIs.

  • Secured $39M in non-dilutive BARDA funding to support antifungal R&D.

  • Strengthened financial position through debt reduction, including CHF14.3M in convertible bond repurchases, and positive operating cash flow.

Financial highlights

  • Total revenue reached CHF104M in H1 2025, up 36% year-on-year, with Cresemba & Zevtera revenue at CHF90.5M (+23.5%).

  • Operating profit surged to CHF24M, a 160% increase year-on-year.

  • Net profit was CHF15.8M, down from CHF20.7M in 2024 due to a one-time tax benefit last year.

  • Net cash position improved to CHF50.7M as of June 30, 2025, from net debt of CHF-26.2M a year earlier.

  • Operating cash flow was CHF23.1M, up from CHF17.9M in 2024.

Outlook and guidance

  • FY 2025 revenue guidance updated to above CHF220M–225M, with Cresemba and Zevtera revenue projected at CHF190M and royalty income expected to grow 14% to CHF110M.

  • Operating profit for 2025 expected at approximately CHF50M, reflecting increased R&D investment.

  • R&D expenses projected to rise to CHF105M, mainly due to in-licensing costs.

  • Anticipate a 17% reduction in product revenue due to decreased supply to Pfizer, offset by royalty growth.

  • Focus on advancing antifungal pipeline, new asset scouting, and maintaining leadership in anti-infectives.

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Frequently asked questions

Basilea Pharmaceutica AG is a biopharmaceutical company specializing in the research, development, and commercialization of hospital anti-infectives and oncology medicines. It focuses on therapies addressing antimicrobial resistance and cancer. The company is headquartered in Basel, Switzerland, and its shares are listed on the SIX Swiss Exchange.

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