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Bioatla (BCAB) investor relations material

Bioatla Q2 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q2 2025 earnings summary7 Aug, 2025

Executive summary

  • Advanced clinical progress for BA3182 (EpCAM x CD3 TCE) and Ozuriftamab vedotin (Oz-V), with tumor reductions and stable disease in solid tumors and high response rates in HPV+ OPSCC; key data readouts expected in 2H 2025 and 1H 2026.

  • Mecbotamab vedotin and evalstotug show promising survival, safety, and efficacy in difficult-to-treat cancers, including mKRAS NSCLC and metastatic melanoma.

  • Strategic partnerships and collaborations are progressing, with at least one term sheet in place and transactions expected to close in 2025.

  • No product revenue recognized; company remains in clinical-stage development with no approved products.

  • Net loss for Q2 2025 was $18.7M, down from $21.1M in Q2 2024; cash and equivalents at June 30, 2025, were $18.2M.

Financial highlights

  • R&D expenses for Q2 2025 were $13.7M, down from $16.2M year-over-year, mainly due to workforce reduction and program prioritization.

  • G&A expenses decreased to $5.0M from $5.8M year-over-year, reflecting lower stock-based compensation and headcount.

  • Net cash used in operations for H1 2025 was $30.4M, down from $50.0M in H1 2024.

  • Net loss per share for Q2 2025 was $0.32, improved from $0.44 in Q2 2024; weighted-average shares outstanding were 58.5M.

  • Total stockholders' equity was $(16.7)M as of June 30, 2025, down from $14.3M at year-end 2024.

Outlook and guidance

  • Phase I data readout for BA3182 expected in 2H 2025, with expansion data in 2026.

  • FDA meeting for Oz-V Phase 3 design in 2L+ HPV+ SCCHN scheduled for Q3 2025; pivotal trial to follow.

  • R&D and cash burn expected to decrease as Phase II trials close and focus shifts to prioritized programs.

  • Additional capital will be required to fund operations beyond the first half of 2026; management is exploring equity, debt, and strategic transactions.

  • No meaningful product revenue expected in the foreseeable future.

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Frequently asked questions

Bioatla Inc is a clinical-stage biopharmaceutical company specializing in the development of novel monoclonal antibody and cell-based therapeutics for the treatment of solid tumor cancers. Utilizing its proprietary Conditionally Active Biologics (CAB) and Comprehensive Integrated Antibody Optimization (CIAO) platforms, Bioatla is focused on creating therapies with improved selectivity for the tumor microenvironment, potentially enhancing safety and therapeutic efficacy. The company is headquartered in San Diego, California, and its shares are listed on the Nasdaq.

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