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Investor Relations14 Oct 2025
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Biofrontera (BFRI) investor relations material
Biofrontera Lytham Partners Fall 2025 Investor Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Lytham Partners Fall 2025 Investor Conference summary30 Sep, 2025
Company overview and product focus
Specializes in photodynamic therapy (PDT) for dermatologic and oncologic indications, primarily actinic keratosis (AK).
Markets Ameluz and RhodoLED lamps, with FDA approval and patent protection until 2043.
Ongoing clinical trials for label expansion into non-melanoma skin cancers and acne.
Over 750 devices placed, integrating doctors into the Ameluz and RhodoLED ecosystem.
Strong efficacy with 91% clearance after one to two treatments for AK.
Financial performance and business model
2024 revenue reached $37.3 million, with long-term gross margin expected at 80%-85%.
Recent transaction to acquire all U.S. IP and NDA rights aims to achieve vertical integration and higher margins.
Year-to-date Q2 2025 revenue was $17.6 million, up from $15.8 million in the prior year.
Gross margin improved to 71% in Q2 2025 from 45% in 2024.
Adjusted EBITDA for 2025 is flat due to one-time legal expenses.
Market opportunity and reimbursement
AK is the top reason for dermatologist visits for those 45+, with a $500M-$520M market opportunity targeted.
Total addressable market for AKs is estimated at $4 billion.
Ameluz has established reimbursement with a J-code and CPT code, with doctors reimbursed $262 per treatment.
Patent protection for nanoemulsion technology extends to 2028, with new formulation patents to 2043.
Future gross margin post-IP acquisition?
What are the next major label expansions?
Ameluz competitive advantages?
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Next Biofrontera earnings date
Q3 202513 Nov, 2025
Next Biofrontera earnings date
Q3 202513 Nov, 2025
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Frequently asked questions
Biofrontera Inc. is a biopharmaceutical company based in the United States, engaged in the commercialization of pharmaceutical products designed to treat dermatological conditions. The company's focus is on photodynamic therapy (PDT) and topical antibiotics. Biofrontera's product portfolio includes Ameluz, a prescription drug for the treatment of actinic keratosis, a common precancerous skin condition, when used in combination with its BF-RhodoLED lamp. Another product, Xepi, is a topical cream approved for the treatment of impetigo, a bacterial skin infection. The company is headquartered in Woburn, Massachusetts, and its shares are listed on the Nasdaq.
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