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BiomX (PHGE) investor relations material
BiomX Q2 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Advanced phage-based clinical programs in cystic fibrosis (BX004) and diabetic foot osteomyelitis (BX211), with BX004 Phase 2b trial initiated and BX211 Phase 2 showing >40% wound size reduction and favorable safety profile.
BX004 Phase 1b/2a data published in Nature Communications, demonstrating ~500-fold bacterial reduction and no resistance in CF patients.
Completed acquisition of Adaptive Phage Therapeutics in March 2024, expanding the pipeline with two Phase 2 assets.
Discontinued atopic dermatitis program and paused prosthetic joint infection program to focus on CF and DFO.
High enthusiasm and accelerated enrollment for BX004 Phase 2b, with strong interest from patients, physicians, and partners.
Financial highlights
Cash and restricted cash totaled $15.2M as of June 30, 2025, down from $18M at year-end 2024, mainly due to operating activities.
Research and development expenses for Q2 2025 were $5.0M, down from $6.9M in Q2 2024, reflecting workforce reductions, lower rent, and increased grant funding.
General and administrative expenses were $2.4M for Q2 2025, down from $2.8M year-over-year, mainly due to reduced legal and professional fees.
Net loss for Q2 2025 was $6.0M, compared to net income of $4.5M in Q2 2024, primarily due to changes in fair value of warrants.
Net cash used in operating activities for the first half of 2025 was $14.8M, down from $22.6M in the same period of 2024.
Outlook and guidance
Cash runway expected to fund operations into Q1 2026; additional capital will be needed for longer-term operations.
Topline results from BX004 Phase 2b in CF expected in Q1 2026; FDA feedback on real-world evidence approach anticipated in H2 2025.
Planning for BX211 registrational study is underway, pending FDA discussions and continued collaboration with the US Defense Health Agency.
No significant product revenue expected in the next twelve months; continued losses anticipated.
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