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Bionano Genomics (BNGO) investor relations material

Bionano Genomics H.C. Wainwright @ Home Event summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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H.C. Wainwright @ Home Event summary15 Oct, 2025

Technology overview and differentiation

  • Optical genome mapping (OGM) analyzes ultra-high molecular weight DNA, enabling detection of large structural variations missed by traditional sequencing.

  • OGM workflow includes DNA isolation, labeling, imaging in proprietary chips, and automated reporting.

  • OGM is complementary to next-generation sequencing (NGS), with mapping for large variants and sequencing for small ones.

  • The VIA software platform integrates OGM, NGS, and microarray data for comprehensive variant analysis.

  • OGM is recognized for high sensitivity and resolution, especially in cell and gene therapy safety applications.

Customer base and market opportunity

  • Main customers are cytogenetic labs in hospitals, academic medical centers, and large reference labs.

  • Approximately 2,500 target labs in the US and Western Europe process about one million samples annually.

  • Applications include blood and bone marrow cancers, constitutional genetic disorders, and cell/gene therapy QC.

  • OGM adoption is growing as a replacement for karyotyping, FISH, and chromosomal microarrays.

  • International expansion is supported by distribution partners, with significant potential in China and other regions.

Product portfolio and revenue drivers

  • Two main instruments: Saphyr (lower volume, $175K) and Stratus (higher volume, $295K, up to 10,000 samples/year).

  • Consumables are the main revenue and profit driver, with software (VIA) offering the highest gross margin.

  • OGM consumables are sold to routine users, with focus on increasing utilization at existing sites.

  • Software is available standalone or bundled, generating recurring revenue from non-OGM users.

  • Installed base is 378 OGM systems, with about 150 in routine cytogenetic use out of 2,500 potential customers.

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Frequently asked questions

Bionano Genomics provides genome analysis software solutions for structural variation discovery and genome assembly enhancement. The Company's Saphyr system is a platform for ultra-sensitive and ultra-specific structural variation detection that enables researchers and clinicians to accelerate the search for new diagnostics and therapeutic targets and to streamline the characterization of these targets. The company was founded in 2003 and is headquartered in San Diego, California.

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