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Botanix Pharmaceuticals (BOT) investor relations material

Botanix Pharmaceuticals Q4 2025 TU earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q4 2025 TU earnings summary27 Jul, 2025

Executive summary

  • Q4 marked the first full quarter post-commercial launch of Softra/Sofdra, targeting primary axillary hyperhidrosis, a large and underserved US market affecting 10 million people.

  • Net revenue surged from $0.7M in Q3 to $4.3M in Q4, with prescriptions shipped up 324% quarter-over-quarter.

  • Unique prescribers increased 115% to 2,316, and new patient arrivals more than doubled to 7,053 in Q4.

  • Sales force expanded from 27 to 33, with further growth planned for FY26 to drive additional market penetration.

  • Focus remains on driving sales, optimizing operational efficiency, and achieving cash flow positivity.

Financial highlights

  • Total prescriptions shipped in Q4 rose 324% to 13,647 from 3,222 in Q3; unique prescribers increased 115% to 2,316.

  • Gross sales reached $20.4M in Q4, up from $4.8M in Q3; unaudited net revenue was $4.3M, up from $0.7M.

  • Operating cash outflow for the quarter was -$28.4M, mainly due to $11.2M in inventory purchases; outflows expected to decline next quarter.

  • Financing cash inflow totaled $65.6M, including $40M equity raise and $30.7M debt drawdown.

  • Year-end cash position was $64.9M, with over $27M in inventory and $15.3M undrawn debt available.

Outlook and guidance

  • Gross to net yield improved to 23% in June, with a target of 30–40% as scale increases.

  • No further significant inventory purchases expected in H1 FY26, supporting lower cash outflows.

  • Revenue expected to rise quarter-on-quarter as market traction grows; company anticipates reaching profitability with current resources.

  • No plans to raise additional capital before reaching cash flow positive, given current cash and expense trends.

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Frequently asked questions

Botanix Pharmaceuticals Limited is a clinical-stage pharmaceutical company focused on developing treatments for dermatological and antimicrobial conditions. The company's pipeline leverages synthetic cannabidiol (CBD) to address skin diseases such as acne, rosacea, and atopic dermatitis, as well as infections caused by antimicrobial-resistant bacteria. Botanix’s products aim to offer innovative therapies that address unmet medical needs, especially in dermatology, by combining novel formulations with delivery systems that enhance drug efficacy. The company is headquartered in North Perth, Australia, and its shares are listed on the ASX.

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