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Brainstorm Cell Therapeutics (BCLI) investor relations material

Brainstorm Cell Therapeutics Q2 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q2 2025 earnings summary14 Aug, 2025

Executive summary

  • Management discussed ongoing business operations and future performance projections, focusing on neurodegenerative disorder treatments and the NurOwn technology platform, with NurOwn as the lead candidate for ALS, PMS, and AD.

  • FDA cleared initiation of the Phase 3b ENDURANCE trial for NurOwn in ALS, aiming for confirmatory data to support a potential BLA submission.

  • Clinical and regulatory progress continues, including FDA alignment on Phase 3b trial design and CMC aspects, and a new manufacturing partnership with Minaris Advanced Therapies.

  • Shares were delisted from Nasdaq and now trade on OTCQB Venture Market as of July 18, 2025.

  • NurOwn pharmacogenomic data was selected as Breakthrough Science at ISCT 2025, highlighting UNC13A genotype impact.

Financial highlights

  • Net loss for Q2 2025 was $2.9M, compared to $2.5M in Q2 2024; net loss for H1 2025 was $5.8M, down from $5.9M in H1 2024.

  • Net loss per share for Q2 2025 was $0.34 (vs. $0.60 in Q2 2024); for H1 2025, $0.77 (vs. $1.35 in H1 2024).

  • Cash, cash equivalents, and restricted cash totaled $1.03M at June 30, 2025.

  • Net cash used in operating activities for H1 2025 was $5.1M; net cash provided by financing activities was $5.8M.

  • Total assets were $2.57M and total liabilities $8.62M as of June 30, 2025, with a stockholders' deficit of $6.06M.

Outlook and guidance

  • Management expects continued operating losses and negative cash flow from clinical and regulatory activities, with additional capital required to fund trials and operations.

  • Focus remains on executing the clinical development plan for NurOwn, with ongoing engagement with clinical sites, CDMO partners, and the ALS community.

  • Anticipates the Phase 3b trial will generate data needed for a new BLA submission.

  • Uncertainty remains regarding the ability to raise future financing, especially after delisting from Nasdaq.

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Brainstorm Therapeutics Inc. engages in the development and commercialization of autologous cellular therapies for the treatment of neurodegenerative diseases.

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