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Cardiol Therapeutics
Cardiol Therapeutics (CRDL) investor relations material
Cardiol Therapeutics TD Cowen 46th Annual Health Care Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.TD Cowen 46th Annual Health Care Conference summary4 Mar, 2026
Strategic focus and pipeline highlights
Targeting inflammation as a key mechanism in heart disease, with late-stage and early-stage programs addressing orphan and broader indications.
MAVERIC, the lead program, is in phase III for recurrent pericarditis, with enrollment accelerating and top-line data expected in late 2024.
ARCHER trial in myocarditis demonstrated the first biological impact by any medicine, supporting the MAVERIC program and opening new opportunities.
All current developments are fully funded, supporting strategic alliances for commercialization.
CRD-38, a next-generation once-monthly subQ formulation, is being advanced for heart failure and attracting strategic partner interest.
Clinical trial results and data
Phase II MAVERIC trial showed rapid, durable pain reduction and significant decrease in pericarditis recurrence, with 71% of patients recurrence-free.
CardiolRx demonstrated normalization of C-reactive protein and sustained efficacy as monotherapy.
ARCHER trial in myocarditis showed a significant reduction in left ventricular mass in just 12 weeks, comparable to leading therapies over longer periods.
CMR improvements in ARCHER align with myocardial recovery and de-risk the MAVERIC phase III program.
Phase III MAVERIC trial design is conservatively powered, aiming for at least 35-40% reduction in recurrence, with phase II having achieved 70%.
Market opportunity and positioning
Immunosuppressants for pericarditis are generating nearly $700 million annually, forecasted to reach $1 billion by 2028, but leave many patients without good options.
CardiolRx aims to be a more accessible, oral, non-immunosuppressive alternative, potentially displacing steroids and preceding IL-1 blockers in treatment algorithms.
Physicians express strong interest in a non-immunosuppressive, oral therapy that could become second-line after NSAIDs and colchicine.
Strategic alliances are being pursued for commercialization and broader market reach.
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Next Cardiol Therapeutics earnings date
Q4 202527 Mar, 2026
Cardiol Therapeutics
Next Cardiol Therapeutics earnings date
Q4 202527 Mar, 2026
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Frequently asked questions
Cardiol Therapeutics Inc. is a biopharmaceutical company focused on developing anti-inflammatory and anti-fibrotic therapies for cardiovascular diseases. The company specializes in small molecule therapeutics targeting conditions such as acute myocarditis, heart failure, and other inflammatory heart disorders. The company is headquartered in Oakville, Ontario, Canada, and its shares are listed on the NASDAQ and TSX.
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