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CareDx (CDNA) investor relations material

CareDx Wells Fargo 20th Annual Healthcare Conference 2025 summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Wells Fargo 20th Annual Healthcare Conference 2025 summary5 Sep, 2025

Strategic opportunities and market outlook

  • Early-stage adoption of molecular monitoring in organ transplantation presents significant growth potential, with increasing standard-of-care acceptance and a long runway for expansion.

  • The company is recognized as an innovator, with a 25-year mission focused on improving patient outcomes through advanced diagnostics and patient-centered solutions.

  • Solutions-based selling, including software, IVD kits, and molecular monitoring, has driven strong adoption, especially in kidney transplant surveillance.

  • Over 60 transplant centers have adopted surveillance protocols, with more than 200 potential programs in the U.S., indicating substantial room for further penetration.

  • Clinical data and published studies are accelerating adoption, with surveillance testing enabling earlier detection and intervention for organ rejection.

Operational execution and technology integration

  • Implementation of Epic EHR integration is expected to streamline administrative processes and support protocol adherence, targeting 10% of volume by year-end and aiming for 50% by the end of next year.

  • Administrative and IT complexities at hospital systems are the main gating factors for broader Epic adoption, but recent perfect implementation scores signal strong execution.

  • Investments in digital solutions, including SaaS transitions and cloud upgrades, are enhancing efficiency and value for transplant centers.

Financial performance and revenue management

  • Revenue cycle management overhaul has improved workflows, automation, and team expertise, targeting a 7% ASP increase to $1,400 by the first half of 2025.

  • Cleaning up legacy claims resulted in a $5 million write-off, but future periods are expected to be free of such negative impacts.

  • Strong balance sheet with no debt and nearly $200 million in cash supports ongoing investments in growth, including a 50% expansion of the sales force.

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Frequently asked questions

CareDx, Inc. discovers, develops, and commercializes diagnostic solutions for transplant patients and caregivers worldwide. It offers UNITY HEART, a precision medicine platform to diagnose the degree of cardiac allograft rejection without the need for a confirmatory endomyocardial biopsy; and UNITY OV, an automated whole blood donor screening system to detect donor-derived cell-free DNA prior to solid organ transplantation and non-invasive as well as categorical monitoring of allograft injury. The company also provides AlloMap heart transplant test that measure mRNA transcripts from 22 genes expressed in immune cells and fibroblasts for personalized patient management; and AlloSure kidney transplant test to measure the amount of a donor specific DNA in a recipient’s bloodstream.

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