CareDx
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CareDx (CDNA) investor relations material

CareDx 47th Annual Raymond James Institutional Investor Conference summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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47th Annual Raymond James Institutional Investor Conference summary3 Mar, 2026

Strategic vision and market overview

  • Focused on enabling transplant patients to thrive through life-changing solutions and expanding beyond solid organ transplantation with the Transplant Plus roadmap.

  • Market leadership in solid organ transplantation, supporting over 200 U.S. transplant centers and performing more than 1 million tests.

  • Total addressable market estimated at $8 billion, with strategic investments in software, medication adherence, and next-generation sequencing kits offered in over 100 countries.

  • Expansion into adjacent markets, including hematologic cancers, with AlloHeme targeting a $1 billion repeat testing opportunity.

Product innovation and clinical integration

  • AlloSure suite provides non-invasive, quantitative monitoring for organ rejection, now standard in many centers' surveillance protocols.

  • Solution selling model drives higher revenue and patient acquisition, with centers adopting multiple products seeing double the testing volume.

  • Broad adoption of software solutions integrated into clinical workflows, including Epic EMR and LIMS consolidation for streamlined ordering and data exchange.

  • Strategic collaboration with 10x Genomics and ImmuneScape program leverages multiomics and spatial biology for future diagnostic development.

Financial performance and outlook

  • Q4 2025 revenue reached $108 million (up 25% YoY), with 53,000 tests performed and a 69% non-GAAP gross margin.

  • Full-year 2025 revenue was $380 million (up 14% YoY), with $201 million in cash and no debt at year-end.

  • Adjusted EBITDA for 2025 was $32 million, up 14%, with significant improvements in cash collections and DSO.

  • 2026 guidance projects $420–$444 million in revenue and $30–$45 million in Adjusted EBITDA, factoring in regulatory changes and continued investment in pipeline and commercial readiness.

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Frequently asked questions

CareDx, Inc. discovers, develops, and commercializes diagnostic solutions for transplant patients and caregivers worldwide. It offers UNITY HEART, a precision medicine platform to diagnose the degree of cardiac allograft rejection without the need for a confirmatory endomyocardial biopsy; and UNITY OV, an automated whole blood donor screening system to detect donor-derived cell-free DNA prior to solid organ transplantation and non-invasive as well as categorical monitoring of allograft injury. The company also provides AlloMap heart transplant test that measure mRNA transcripts from 22 genes expressed in immune cells and fibroblasts for personalized patient management; and AlloSure kidney transplant test to measure the amount of a donor specific DNA in a recipient’s bloodstream.

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