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Cartesian Therapeutics (RNAC) investor relations material
Cartesian Therapeutics Q3 2026 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Descartes-08 is advancing in Phase 3 AURORA for myasthenia gravis (MG), with a 1Q27 data readout targeted and a BLA filing planned for mid-2027; Phase 2 TRITON is evaluating myositis.
Cash, cash equivalents and restricted cash totaled $124.7M at September 30, 2026, and are expected to fund planned operations into 2028, including completion of AURORA.
Q3 net loss narrowed to $11.5M from $35.9M, chiefly reflecting non-cash fair-value gains on CVR and derivative liabilities, while trial spending increased.
Financial highlights
Q3 revenue was $0 versus $0.5M in Q3 2025; 9M revenue was $0.1M versus $1.85M, reflecting lower grant revenue and no collaboration or license revenue.
Q3 operating expenses were $25.0M, up 16% YoY; R&D was $15.6M versus $13.8M and G&A was $9.4M versus $7.7M.
Q3 operating loss was $25.0M versus $21.1M; 9M operating loss was $80.7M versus $64.8M.
Q3 net loss was $11.5M versus $35.9M; 9M net loss was $34.9M versus $37.7M. Q3 included $10.7M CVR and $3.3M derivative fair-value gains.
9M operating cash use was $70.9M versus $56.2M; investing cash use was $0.7M versus $5.0M.
Outlook and guidance
AURORA data readout is targeted for 1Q27, followed by a BLA filing planned for mid-2027.
TRITON subset data and HELIOS data are expected in 1H27; TRITON results are intended to inform the potential path to a pivotal myositis trial.
Current cash resources are expected to support planned operations into 2028.
Operating losses and R&D and G&A expenses are expected to continue increasing; product-sales revenue is not expected for at least several years, and profitability may never be achieved.
- Q2 2026 net income was $15.8M, with a six-month net loss of $23.4M and cash runway into 2028.RNAC
Q2 2026 - Directors elected and all proposals passed with strong support; no stockholder questions submitted.RNAC
AGM 2026 - Q1 2026 net loss rose to $39.2M as R&D and CVR liability increased; cash at $120.4M.RNAC
Q1 2026 - Virtual annual meeting to vote on directors, pay, and auditor ratification June 12, 2026.RNAC
Proxy filing - 2026 proxy covers director elections, executive pay, auditor ratification, and governance priorities.RNAC
Proxy filing - Descartes-08 delivers durable, outpatient mRNA cell therapy for autoimmune diseases, targeting major US markets.RNAC
Corporate presentation - Net loss rose to $130.3M in 2025 as pivotal Descartes-08 trials advanced; cash runway extends to mid-2027.RNAC
Q4 2025 - Up to $400M in securities, including $100M at-the-market stock, to fund mRNA autoimmune pipeline.RNAC
Registration Filing - Over 11 million shares registered for resale as mRNA cell therapy pipeline advances.RNAC
Registration Filing
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Next Cartesian Therapeutics earnings date
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