Cartesian Therapeutics
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Cartesian Therapeutics (RNAC) investor relations material

Cartesian Therapeutics Q3 2026 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2026 earnings summary5 Nov, 2026

Executive summary

  • Descartes-08 is advancing in Phase 3 AURORA for myasthenia gravis (MG), with a 1Q27 data readout targeted and a BLA filing planned for mid-2027; Phase 2 TRITON is evaluating myositis.

  • Cash, cash equivalents and restricted cash totaled $124.7M at September 30, 2026, and are expected to fund planned operations into 2028, including completion of AURORA.

  • Q3 net loss narrowed to $11.5M from $35.9M, chiefly reflecting non-cash fair-value gains on CVR and derivative liabilities, while trial spending increased.

Financial highlights

  • Q3 revenue was $0 versus $0.5M in Q3 2025; 9M revenue was $0.1M versus $1.85M, reflecting lower grant revenue and no collaboration or license revenue.

  • Q3 operating expenses were $25.0M, up 16% YoY; R&D was $15.6M versus $13.8M and G&A was $9.4M versus $7.7M.

  • Q3 operating loss was $25.0M versus $21.1M; 9M operating loss was $80.7M versus $64.8M.

  • Q3 net loss was $11.5M versus $35.9M; 9M net loss was $34.9M versus $37.7M. Q3 included $10.7M CVR and $3.3M derivative fair-value gains.

  • 9M operating cash use was $70.9M versus $56.2M; investing cash use was $0.7M versus $5.0M.

Outlook and guidance

  • AURORA data readout is targeted for 1Q27, followed by a BLA filing planned for mid-2027.

  • TRITON subset data and HELIOS data are expected in 1H27; TRITON results are intended to inform the potential path to a pivotal myositis trial.

  • Current cash resources are expected to support planned operations into 2028.

  • Operating losses and R&D and G&A expenses are expected to continue increasing; product-sales revenue is not expected for at least several years, and profitability may never be achieved.

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Frequently asked questions

Cartesian Therapeutics Inc is a clinical-stage biopharmaceutical company focused on developing cell therapies for the treatment of autoimmune diseases and cancer. The company uses its proprietary RNA cell therapy platform to engineer immune cells with therapeutic potential. Cartesian’s therapies are designed to target specific disease pathways, aiming to provide more effective treatments with fewer side effects compared to traditional approaches. The company is headquartered in Gaithersburg, Maryland, and its shares are listed on the NASDAQ.