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CelLBxHealth plc (AGL) investor relations material

CelLBxHealth plc H1 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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H1 2025 earnings summary9 Sep, 2025

Executive summary

  • Successfully completed three large pharma contracts and signed a major medtech collaboration with Myriad Genetics, expanding clinical and commercial opportunities despite revenue pressure from adverse market conditions.

  • Advanced DNA dual analysis workflow for CTC-DNA and ctDNA, and demonstrated integration with Illumina sequencing for enhanced cancer mutation detection.

  • NHS engagement for blood-based cancer diagnostics, with ongoing clinical lab accreditation and discussions with large pharma and medtech companies.

  • Eleven new peer-reviewed publications and pivotal research in cancer metastasis, including Nature Medicine publication on cluster buster drugs.

  • Over 270 Parsortix systems in use and more than 248,000 samples processed as of 30 June 2025.

Financial highlights

  • H1 2025 revenue was £0.8 million, down from £1.0 million in H1 2024, due to customer delays and challenging macro conditions.

  • Gross margin remained stable at 59% year-over-year.

  • Operating expenditure reduced by 12% to £8.0 million, and comprehensive loss reduced by 7% year-over-year.

  • Cash and R&D tax credits position at £6.6 million, with cash and cash equivalents at £5.3 million as of 30 June 2025; cash runway extends into Q1 2026.

  • Loss per share for H1 2025 was 2.87p, compared to 2.89p in H1 2024.

Outlook and guidance

  • Revenue for 2025 expected to exceed £1.5 million, with delays likely shifting further revenue into 2026.

  • Focus on securing additional funding in H2 from commercial milestones, collaborations, and potential equity or debt.

  • Anticipation of clinical lab accreditation by year-end to enable direct patient testing.

  • Pipeline includes multiple large pharma and medtech opportunities, NHS clinical studies, and new contracts.

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Frequently asked questions

ANGLE plc is a British medical diagnostics company focused on developing liquid biopsy solutions for cancer diagnostics. The company’s proprietary Parsortix system enables the capture and analysis of circulating tumor cells (CTCs) from patient blood samples, allowing for non-invasive cancer detection, monitoring, and personalized treatment insights. ANGLE’s technology is used in clinical research and trials, supporting advancements in oncology by providing real-time data on tumor progression and response to therapy. The company is headquartered in Guildford, United Kingdom, and its shares are listed on the London Stock Exchange and the Nasdaq.

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