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Century Therapeutics (IPSC) investor relations material
Century Therapeutics H.C. Wainwright 27th Annual Global Investment Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.H.C. Wainwright 27th Annual Global Investment Conference summary5 Sep, 2025
Strategic transformation and pipeline prioritization
Over the past six months, a focused transformation has prioritized programs with the highest market potential, optimizing capital and resources.
Core pipeline programs are being accelerated, all engineered with proprietary AlloVision technology.
Emphasis on both immune and non-immune cell programs, with a non-immune cell candidate nearing drug candidacy.
Cash runway extends into Q4 2027, supporting progress beyond key clinical milestones.
Technology platforms and innovation
AlloVision technology enables enhanced persistence and re-dosing by providing immune evasion through multiple genetic edits.
AlloVision 5.0 incorporates pan-NK inhibitory ligand CD300a and an IgG-degrading protease for broad immune protection.
Preclinical data show CD300a taser provides protection across diverse NK cell types, outperforming CD47-based approaches.
IgG-degrading enzyme eliminates complement-dependent cytotoxicity and antibody-dependent cellular phagocytosis.
Progress in iPSC-derived T cell therapies
Developed iPSC-derived alpha-beta T cells (CD4/CD8) functionally comparable to primary T cells, addressing a major field challenge.
Century 308, a CD19-targeted CARiT therapy, shows in vitro and in vivo efficacy, persistence, and tumor control similar to primary CAR T cells.
Four-stage differentiation process enables tunable CD4/CD8 T cell mix, essential for effective immunotherapy.
Preclinical studies demonstrate robust cytotoxicity, IL-2 secretion, and expansion upon target engagement.
What insights led to Century's strategic shift?
How does AlloVision 5.0 provide holistic protection?
How does Century 308 address autologous CAR T access?
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Next Century Therapeutics earnings date
Chardan’s 9th Annual Genetic Medicines Conference21 Oct, 2025
Next Century Therapeutics earnings date
Chardan’s 9th Annual Genetic Medicines Conference21 Oct, 2025
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Frequently asked questions
Century Therapeutics Inc. is a biotechnology company focused on developing innovative cell therapy products. The company specializes in the creation of allogeneic cell therapies derived from induced pluripotent stem cells (iPSCs). These therapies are designed to treat a range of conditions, including solid tumors and hematological malignancies. Century Therapeutics' leading product candidates include therapies targeting specific cancer markers, such as CD19 and Nectin-4, and are developed through advanced gene editing and cellular engineering technologies. The company is headquartered in Philadelphia, Pennsylvania, and its shares are listed on the NASDAQ.
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