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Century Therapeutics (IPSC) investor relations material
Century Therapeutics Piper Sandler 37th Annual Healthcare Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Piper Sandler 37th Annual Healthcare Conference summary3 Dec, 2025
Key program updates and pipeline progress
Advancing iPSC-derived cell therapies, including CAR T, CAR NK, and beta islet cells for autoimmune diseases, cancer, and type 1 diabetes.
Beta islet cell program (CNTY813) aims to treat type 1 diabetes with reduced or no chronic immunosuppression, targeting IND-enabling studies by year-end and IND submission as early as next year.
CD19 CAR-iT (CNTY-308) is set to enter clinical trials next year, focusing initially on autoimmune diseases with potential for reduced or no lymphodepletion.
Phase 1 Carmel study of CD19 CAR-NK (CNTY-101) in multiple autoimmune diseases is ongoing, with initial safety and translational data expected at an upcoming conference.
Discontinued Calypso study to focus resources on more promising programs and partnerships.
Scientific and technological innovations
Alloevasion 5.0 platform enables iPSC-derived cells to evade both cellular and humoral immune responses, using unique edits such as a universal NK cell inhibitory ligand and an IgG-degrading protease.
Preclinical studies show the IgG-degrading protease effectively eliminates antibody-mediated immune attack without systemic IgG depletion.
iPSC cell foundry allows direct differentiation into various cell types, supporting scalable and reproducible manufacturing.
Strategic focus and future directions
Emphasis on scalable manufacturing to address large patient populations in autoimmune diseases and type 1 diabetes.
Ongoing and potential future partnerships with pharma to expand access and leverage Alloevasion technology in new fields.
Exploring regenerative medicine applications beyond immune cell types, such as dopaminergic neurons for Parkinson’s and heart muscle cells for cardiac disease.
Detail Alloevasion's unique IgG degrading protease
How does CNTY813 aim to reduce immunosuppression?
How will 308 address autoimmune disease scale?
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Next Century Therapeutics earnings date
Q4 202513 Mar, 2026
Next Century Therapeutics earnings date
Q4 202513 Mar, 2026
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Frequently asked questions
Century Therapeutics Inc. is a biotechnology company focused on developing innovative cell therapy products. The company specializes in the creation of allogeneic cell therapies derived from induced pluripotent stem cells (iPSCs). These therapies are designed to treat a range of conditions, including solid tumors and hematological malignancies. Century Therapeutics' leading product candidates include therapies targeting specific cancer markers, such as CD19 and Nectin-4, and are developed through advanced gene editing and cellular engineering technologies. The company is headquartered in Philadelphia, Pennsylvania, and its shares are listed on the NASDAQ.
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