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Charles River Laboratories (CRL) investor relations material
Charles River Laboratories Evercore ISI 8th Annual HealthCONx Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Evercore ISI 8th Annual HealthCONx Conference summary3 Dec, 2025
Business performance and demand trends
Book-to-bill ratio has improved sequentially since the start of Q3, reflecting positive momentum despite potential holiday impacts.
Biotech funding surged in the third quarter, with last month marking the second-best month ever for biotech funding.
Pharma demand remains stable, supported by long-term contracts and robust spending, but cannot fully offset biotech sluggishness.
Proposal volume is up and cancellations are down for both biotech and pharma, indicating increased client confidence.
Operational initiatives and cost management
Additional hiring in lab services aligns with strong demand and the need to replace turnover, supporting raised guidance.
Higher spot NHP costs are due to increased demand exceeding initial supply plans, despite overall cost reductions and diversified sourcing.
$70 million in incremental DSA costs will be managed through labor, procurement efficiency, offshoring, and automation, mainly to offset inflation.
Portfolio strategy and M&A/divestitures
A deep portfolio review led to plans to divest about 7% of revenue from non-core assets, focusing on businesses with persistent headwinds.
Proceeds from divestitures may be used for M&A, debt repayment, or share buybacks, with several acquisition targets under consideration.
Bioanalysis and lab services are flagged for organic investment and potential M&A, responding to strong client demand.
Exploring non-animal in vitro NAMs technologies and considering geographic expansion, especially in China, due to rising innovation and market potential.
Divestiture criteria and reinvestment plans
China market re-entry strategy and opportunities
NAMs impact on safety testing and FDA guidance?
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Next Charles River Laboratories earnings date
Q4 202518 Feb, 2026
Next Charles River Laboratories earnings date
Q4 202518 Feb, 2026
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Frequently asked questions
Charles River Laboratories International, Inc. is a concract research organization providing drug discovery, non-clinical development and safety testing services in the United States, Europe, Canada and the Asia Pacific regions. The Company provides research models and related services to support clients from target identification through non-clinical development. The Company operates through three segments: Research Models and Services (RMS), Discovery and Safety Assessment (DSA), and Manufacturing Support.
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