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Cinclus Pharma (CINPHA) investor relations material

Cinclus Pharma KOL Event summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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KOL Event summary11 Dec, 2025

Introduction and agenda

  • Event focused on linaprazan glurate, a next-generation PCAB, and its role in addressing unmet needs in GERD, especially severe erosive GERD.

  • Agenda included a KOL overview of GERD, limitations of current therapies, real-world patient cases, and a commercial landscape discussion.

KOL background and credentials

  • Dr. Prateek Sharma, Professor of Medicine, is internationally recognized for advancing GI disease management and has over 550 publications in top journals.

  • He is a frequent speaker at major scientific meetings and has contributed to clinical guidelines and textbooks.

Market insights and analysis

  • GERD affects about 20% of the U.S. population and 14% globally, with significant impact on quality of life and work productivity.

  • Erosive GERD, especially grades C and D, is associated with higher risks of complications like Barrett's esophagus and esophageal cancer.

  • The severe erosive GERD market in the USA and Europe is estimated at 10 million patients, representing a large, dynamic, and chronic market with frequent drug switching.

  • PCABs are gaining traction globally, with premium pricing and rapid uptake in markets like Japan and the U.S.

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Q4 202518 Feb, 2026
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Frequently asked questions

Cinclus Pharma Holding AB is a clinical-stage pharmaceutical company based in Stockholm, Sweden. The company specializes in the development of treatments for acid-related diseases. Its primary focus is on a drug candidate called linaprazan glurate, which is being developed for the treatment of gastroesophageal reflux disease (GERD) and Helicobacter pylori infections. Linaprazan glurate is designed as a Potassium-Competitive Acid Blocker (P-CAB), offering a potentially more effective alternative to traditional Proton Pump Inhibitors (PPIs) used in treating acid-related conditions. Cinclus Pharma Holding AB is headquartered in Stockholm, Sweden, and its shares are listed on the Nasdaq Stockholm.

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