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Circio
Circio (CRNA) investor relations material
Circio Status update summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Status update summary15 Jan, 2026
Technology platform and innovation
Developed a proprietary circular RNA (circVec) platform enabling enhanced and prolonged gene expression for gene and cell therapy applications.
circVec offers up to 75x longer half-life and 40x higher protein expression in vivo compared to conventional mRNA approaches.
Demonstrated significant improvements in heart, eye, and CNS gene expression, with up to 40x increased activity in heart tissue.
circVec enables dose reduction in AAV gene therapy, lowering toxicity and cost while maintaining efficacy.
In vivo cell therapy applications show >6 months expression duration, outperforming mRNA-based approaches.
Market opportunity and partnerships
Targeting large patient populations in heart, eye, and CNS genetic diseases, as well as cancer and autoimmune disorders.
Recent industry deals in AAV gene therapy and in vivo cell therapy highlight strong commercial interest, with transactions up to $2.1 billion.
Entered first partnership with a global pharma company in Q4 2025, with additional collaborations targeted.
Financial update and rights issue
Announced an 88% underwritten and presubscribed NOK 50 million rights issue, priced at NOK 1.00 per share.
Rights issue supported by major shareholders, with NOK 24.2 million in presubscription commitments.
Funds will support operations for 12 months and enable delivery of key pre-clinical milestones, including a feasibility study with a major pharma partner.
Subscription period runs from 15–29 January 2026, with attached warrants exercisable in June 2026.
Quantify circVec's AAV expression advantage
Detail current pharma collaboration scope
What data triggers future partnering interest?
Partial view of Summaries dataset, powered by Quartr API
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Next Circio earnings date
Q4 202510 Apr, 2026
Circio
Next Circio earnings date
Q4 202510 Apr, 2026
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Frequently asked questions
Circio Holding ASA, formerly known as Targovax ASA, is a biotechnology company primarily engaged in the development of innovative circular RNA (circRNA) and immunotherapy medicines. The company has pioneered a distinctive circRNA platform, aiming to create novel circRNA medicines for a variety of applications including rare diseases, vaccines, cancer treatments, protein replacement therapies, and cell therapy. The company is headquartered in Oslo, Norway, and its shares are listed on the Oslo Stock Exchange under the ticker symbol CRNA.
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