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Clearpoint Neuro (CLPT) investor relations material
Clearpoint Neuro Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q3 2025 earnings summary6 Nov, 2025
Executive summary
Announced a strategic merger agreement to acquire IRRAS Holdings, Inc., expanding into neurocritical care and cranial irrigation markets, and enhancing operational scale with a combined commercial team of over 50 professionals.
Revenue for Q3 2025 increased 9% year-over-year to $8.9 million, driven by growth in service revenue and neurosurgery navigation and therapy sales.
Supported over 60 biopharma partners, with nine programs accepted for FDA expedited review and expanded global regulatory clearances to 34 countries.
Transitioned to a two-part growth strategy: "fast forward" to penetrate existing billion-dollar markets and "essential everywhere" to build a new multi-billion-dollar neurodrug delivery market.
Demonstrated a prototype Robotic Neuro-Navigation System and received FDA clearance for PRISM Laser Therapy System compatibility with 1.5T MRI, expanding addressable market.
Financial highlights
Q3 2025 revenue was $8.9 million, up 9% year-over-year from $8.1 million in Q3 2024.
Gross margin improved to 63% from 60% in the prior year quarter, driven by higher service margins and favorable product mix.
Cash and equivalents stood at $38.2 million as of September 30, 2025, up from $20.1 million at year-end 2024, reflecting $32 million in new financing offset by $11.8 million in operating cash use.
Net loss for Q3 2025 was $5.9 million, compared to $5.0 million in Q3 2024, with net loss per share of $(0.21).
Operating expenses increased 9% to $10.9 million, driven by R&D, professional services, and personnel costs.
Outlook and guidance
2025 full-year revenue forecast narrowed to $36–$38 million, in line with prior guidance.
Post-merger, 2026 revenue for the combined entity expected between $54–$60 million, with further updates after integration.
Biologics and drug delivery expected to return to double-digit growth in Q4 2025 and accelerate in 2026–2027.
Cash reserves projected to be sufficient to support operations for at least the next twelve months.
Long-term vision targets $500 million annual revenue and 70% gross margins.
IRRAS acquisition's impact on cash breakeven
How will site activation drive C> commercialization?
CAL facility's impact on Biologics revenue growth
What are the key operational synergies from IRRAS?
How will ClearPoint derisk cell/gene therapy supply?
New CRO facility: magnitude of future studies?
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Next Clearpoint Neuro earnings date
Q4 202525 Feb, 2026
Next Clearpoint Neuro earnings date
Q4 202525 Feb, 2026
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Frequently asked questions
ClearPoint Neuro, Inc. operates as a medical device company primarily in the United States. The company develops and commercializes platforms for performing minimally invasive surgical procedures in the brain under direct, and intra-procedural magnetic resonance imaging guidance. It offers ClearPoint software, a platform that provides direct visualization of MRI that enables physicians to image the patient's brain in real-time;
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