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Clearside Biomedical (CLSD) investor relations material

Clearside Biomedical Q2 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q2 2025 earnings summary8 Aug, 2025

Executive summary

  • Announced a strategic review in July 2025, pausing all internal R&D and transitioning all employees to consulting roles to conserve cash and explore alternatives including sale, merger, or asset divestiture.

  • Net loss narrowed to $4.5M for Q2 2025 from $7.6M in Q2 2024; six-month net loss was $12.7M, down from $19.4M year-over-year.

  • Cash and cash equivalents were $9.4M as of June 30, 2025, with substantial doubt about the ability to continue as a going concern for the next 12 months.

Financial highlights

  • Q2 2025 revenue was $0.5M, up from $90K in Q2 2024, mainly from license agreements and SCS Microinjector kit sales.

  • Research and development expenses dropped to $1.6M in Q2 2025 from $4.6M in Q2 2024, reflecting the completion of a major clinical trial and cost reductions.

  • General and administrative expenses decreased to $2.5M in Q2 2025 from $3.1M in Q2 2024, primarily due to lower employee-related costs.

  • Non-cash interest expense on royalty liability was $2.8M in Q2 2025, up from $2.3M in Q2 2024.

  • Net cash used in operations for the first half of 2025 was $10.6M, down from $13.5M in the prior year period.

Outlook and guidance

  • Strategic alternatives under review include sale, licensing, monetization, partnership, or winding down if no viable option is found.

  • All internal R&D programs are paused and may resume only if additional capital is raised.

  • Company does not expect current cash to fund operations for the next 12 months; additional financing is required.

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Frequently asked questions

Clearside Biomedical, Inc. is a biopharmaceutical company specializing in the development of therapies for the treatment of eye diseases. The company focuses on treating conditions affecting the retina and choroid through its proprietary SCS Microinjector platform, which delivers drugs directly to the back of the eye. Clearside's approach aims to enhance the efficacy of treatments for serious vision-threatening diseases, including macular edema and uveitis. The company is headquartered in Alpharetta, United States, and its shares are listed on the NASDAQ.

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