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Clinical Laserthermia Systems (CLS) investor relations material

Clinical Laserthermia Systems Q3 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2025 earnings summary14 Nov, 2025

Executive summary

  • Achieved FDA clearance for expanded labeling of the ClearPoint Prism Neuro Laser Therapy System, doubling the addressable U.S. market for neurosurgery applications.

  • Positive clinical safety study results for laser ablation in malignant brain tumor patients, showing increased median survival versus open surgery.

  • Strategic focus on neurosurgery segment and partnership expansion outside neurosurgery to diversify revenue and reduce risk.

Financial highlights

  • Q3 2025 revenue was SEK 2.8 million, down from SEK 5.4 million year-over-year, mainly due to timing of deliveries and lower urology sales.

  • Operating profit improved by SEK 2.3 million in Q3 and by SEK 21.4 million for the first nine months compared to the same periods last year.

  • Net loss for Q3 was SEK -8.1 million, improved from SEK -13.0 million in Q3 2024; nine-month net loss was SEK -29.7 million, better than SEK -39.0 million last year.

  • Earnings per share for Q3 was SEK -0.3, compared to SEK -1.0 in Q3 2024.

  • Equity ratio increased to 89% at the end of Q3 2025 from 85% a year earlier.

Outlook and guidance

  • Priorities include accelerating U.S. adoption of the Prism system, advancing regulatory initiatives in Europe, expanding partnerships outside neurosurgery, and optimizing margins.

  • Targeting positive cash flow by end of 2026 through focus on neurosurgery commercialization and cost efficiency.

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Frequently asked questions

Clinical Laserthermia Systems AB is a Swedish medical technology company focused on developing minimally invasive laser-based treatment systems for cancer and neurosurgery. The company’s flagship product is the TRANBERG Thermal Therapy System, which is designed for precision laser ablation of solid tumors. This system enables high-precision, image-guided treatments for conditions such as prostate cancer and brain lesions. CLS is also advancing imILT (immunostimulating interstitial laser thermotherapy), which combines laser ablation with immune system stimulation to treat various types of tumors, including those in the liver, lungs, and pancreas. The company is headquartered in Lund, Sweden, and its shares are listed on the Stockholm Stock Exchange.

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