Cognition Therapeutics
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Cognition Therapeutics (CGTX) investor relations material

Cognition Therapeutics Q3 2026 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2026 earnings summary5 Nov, 2026

Executive summary

  • FDA feedback aligned key elements of a planned zervimesine registrational study in DLB, with a mid-2027 start targeted.

  • Q3 net loss narrowed year over year to $4.1M; cash, grants and offering proceeds are expected to support operations into Q4 2027, assuming no 2025 ATM use.

Financial highlights

  • Q3 2026 R&D expense was $5.1M vs. $3.8M in Q3 2025, driven by higher CRO trial activity and professional fees.

  • Q3 2026 G&A expense was $2.3M vs. $2.6M in Q3 2025, primarily reflecting lower professional fees and compensation.

  • Q3 net loss was $4.1M, or $0.04 per basic and diluted share, vs. $4.9M, or $0.06 per share, in Q3 2025.

  • 9M operating expenses were $23.9M vs. $34.1M; net loss was $12.6M vs. $20.1M year over year.

  • Q3 operating expenses were $7.4M vs. $6.4M; total other income, primarily grants, was $3.2M vs. $1.4M.

Outlook and guidance

  • START enrolled 545 participants; top-line results in mild cognitive impairment and early Alzheimer’s disease are expected in H2 2027, after all participants complete 18 months of treatment.

  • Current cash is expected to fund operations and capital expenditures into Q4 2027; the estimate includes non-dilutive grants and offering proceeds and assumes no 2025 ATM use.

  • Manufacturing, site selection, patient recruitment and protocol finalization remain under evaluation for the planned DLB study.

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Frequently asked questions

Cognition Therapeutics Inc. is a clinical-stage biopharmaceutical company dedicated to discovering and developing small molecule therapeutics aimed at treating age-related degenerative diseases and disorders affecting the central nervous system and retina. The company's research focuses on developing a portfolio of small molecule product candidates targeting the sigma-2 receptor (S2R) complex. This receptor complex is a crucial regulator of the cellular damage response for conditions such as Alzheimer's disease , dry age-related macular degeneration (dry AMD), geographic atrophy, among others. Cognition Therapeutics is headquartered in Purchase, New York, and its shares are listed on the Nasdaq.