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Coherus BioSciences (CHRS) investor relations material
Coherus BioSciences UBS Virtual Oncology Day summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
Strategic overview and pipeline
Focused on improving cancer patient survival with a three-part strategy: marketed drugs, pipeline development, and strategic partnerships.
Lead assets include LOQTORZI (PD-1 inhibitor), CHS-114 (anti-CCR8 antibody), and casdozokitug (anti-IL-27 antibody).
Key data readouts expected around mid-2026 for multiple tumor types, including head and neck, gastric, esophageal, and colorectal cancers.
Actively seeking ex-US partners for pipeline validation and cost-sharing.
Strong financial track record with growth in sales, balance sheet management, and deal revenue.
LOQTORZI (PD-1 inhibitor) insights
LOQTORZI shows over tenfold higher binding affinity than other PD-1s and unique epitope binding, leading to increased activity.
Demonstrates similar efficacy in both PD-L1 high and low patients, differentiating it from competitors.
Approved in frontline and second-line nasopharyngeal carcinoma, with preferred NCCN guideline positioning.
Projected to reach $150–200 million peak sales by mid-2028, with 10–15% quarterly growth expected.
Combination strategy leverages partnerships and internal pipeline assets to expand indications and revenue.
Combination and expansion strategies
Collaborative approach allows LOQTORZI to be included in partner clinical trials, gaining new labels at low cost.
Internal pipeline assets (CHS-114, casdozokitug) are being developed in combination with LOQTORZI.
Demonstrated combinability with chemotherapy, IO agents, and ADCs; phase III data in bladder cancer to be presented.
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