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Coherus Oncology (CHRS) investor relations material
Coherus Oncology Jefferies London Healthcare Conference 2025 summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Jefferies London Healthcare Conference 2025 summary18 Nov, 2025
Strategic overview and value proposition
Focus on innovative oncology with a pipeline built around drugs, data, and deals.
LOQTORZI, a next-generation PD-1, serves as a foundational product and revenue multiplier.
Pipeline includes CHS-114 (Treg depleter) and casdozokitug (anti-IL-27), targeting multiple cancer types.
Global rights to pipeline assets enable both U.S. and ex-U.S. licensing opportunities.
Divestiture of biosimilars generated significant capital, enabling focus on oncology innovation.
Pipeline development and clinical progress
LOQTORZI approved for nasopharyngeal cancer, with ongoing studies in head and neck, GI, and other cancers.
CHS-114 studies underway in colorectal, gastric, and head and neck cancers, with data expected 2025–2026.
Casdozokitug shows promising data in liver and lung cancers, with further expansion planned.
Pipeline addresses a $30 billion U.S. market opportunity across multiple indications.
Data readouts for key studies anticipated mid-2026 and beyond.
Scientific innovation and differentiation
LOQTORZI demonstrates efficacy in both low and high PD-L1 states, outperforming competitors in certain settings.
CHS-114 is highly selective for CCR8, minimizing off-target effects seen in competitor molecules.
First clinical evidence that Treg depletion leads to CD8+ T cell infiltration and tumor response.
Casdozokitug targets IL-27, modulating immune checkpoints and activating natural killer cells.
Strong safety profiles and promising response rates observed in early studies.
LOQTORZI's low PD-L1 efficacy: market impact?
CHS-114's selectivity: what competitive edge?
Casdozokitug's 17% CR rate: how to leverage?
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Next Coherus Oncology earnings date
Biotech Discovery Series17 Dec, 2025
Next Coherus Oncology earnings date
Biotech Discovery Series17 Dec, 2025
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Frequently asked questions
Coherus BioSciences, Inc., a biopharmaceutical company, focuses on the biosimilar and immuno-oncology market primarily in the United States. The company seeks to create rationally designed molecules for important therapeutic targets that have been the targets of drugs or biological products that are either currently approved or in clinical development for inflammatory, metabolic, autoimmune/lupus, nephrology and cardiovascular/vascular diseases. Coherus BioSciences was founded in 2010 and is headquartered in Redwood City, California.
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