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Compugen (CGEN) investor relations material

Compugen Q3 Investor Summit Group Virtual Conference 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 Investor Summit Group Virtual Conference 2025 earnings summary16 Sep, 2025

Strategic direction and leadership

  • Transition in leadership with Eran Ophir becoming President and CEO, while Anat Cohen-Dayag moves to Executive Chairperson.

  • Focus on AI-driven computational biology to identify novel immuno-oncology drug targets.

  • Emphasis on innovation for patients with unmet needs in cancer treatment.

  • Strong scientific expertise and culture of innovation highlighted as growth drivers.

Pipeline and clinical progress

  • Two fully owned clinical-stage assets: COM701 (anti-PVRIG) and COM902 (anti-TIGIT, FC-non-active).

  • COM701 in a new randomized study for platinum-sensitive ovarian cancer; readout expected in H2 2026.

  • COM902 positioned as the only non-partnered FC-non-active TIGIT antibody, with potential value from ongoing phase III trials by partners.

  • Additional assets in early pipeline derived from the Unigen™ platform.

Partnerships and financial outlook

  • Collaborations with AstraZeneca and Gilead validate the platform and provide over $1 billion in potential future milestones.

  • AstraZeneca's rifleucostamid in 10 phase III trials, with predicted sales over $5 billion and mid-single-digit tiered royalties.

  • Gilead collaboration on GS0321, with $90 million received and up to $758 million in future milestones, plus tiered royalties.

  • Stable cash balance of $94 million as of June 30, with runway into 2027.

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Frequently asked questions

Compugen Ltd. is a clinical-stage therapeutic discovery and development company that focuses on immuno-oncology and autoimmune diseases. The company leverages a predictive computational discovery platform to identify novel drug targets and develop therapeutic products. Its pipeline includes a range of products in clinical trials, such as COM701 and COM902, which target various cancers including non-small cell lung cancer and head and neck squamous cell carcinoma. The company is headquartered in Holon, Israel, and its shares are listed on the NASDAQ.

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