Corvus Pharmaceuticals
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Corvus Pharmaceuticals (CRVS) investor relations material

Corvus Pharmaceuticals 12th Annual Cantor Fitzgerald Global Healthcare Conference summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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12th Annual Cantor Fitzgerald Global Healthcare Conference summary10 Sep, 2026

Company overview and lead program

  • Focuses on novel immune modulators for cancer and immune diseases, with soquelitinib as the lead oral ITK inhibitor in phase III for PTCL and phase II for atopic dermatitis.

  • Soquelitinib is also being studied in China by a partner and will expand into asthma and HS trials this year.

  • Strong patent protection extends to 2042 with pharmaceutical extensions.

  • ITK platform supports a pipeline of next-generation and backup compounds.

Mechanism of action and differentiation

  • Soquelitinib is an oral tablet, offering an alternative to injectable therapies in atopic dermatitis.

  • Blocks Th2 and Th17 pathways, reducing key cytokines and increasing Treg cells, rebalancing rather than suppressing the immune system.

  • Highly selective for ITK, with limited off-target effects and a strong safety profile.

  • No observed immunosuppression or infection risk due to sparing of RLK pathway.

Clinical and biomarker data

  • Safety profile in atopic dermatitis is similar to placebo; efficacy is comparable to JAK inhibitors or biologics depending on endpoint.

  • Biomarker data show dose-dependent reduction in Th2/Th17 cytokines and increased Treg cells, with effects persisting off therapy.

  • Clinical effect maintained up to 90 days post-therapy; durability to be further studied in ongoing trials.

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Frequently asked questions

Corvus Pharmaceuticals Inc. is a clinical-stage biopharmaceutical company focused on developing immune-oncology therapies for the treatment of cancer and immune-related diseases. The company’s pipeline includes drug candidates that target key immune pathways to enhance the body’s immune response against cancer cells. The company is headquartered in Burlingame, California, and its shares are listed on the NASDAQ.